Protein Alignment CG40486 and RDH8

DIOPT Version :9

• Sequence 1: NP_001036311.2
• Gene: CG40486 / 3355162
• FlyBaseID: FBgn0263830
• Length: 247
• Species: Drosophila melanogaster
• Sequence 2: NP_056540.3
• Gene: RDH8 / 50700
• HGNCID: 14423
• Length: 311
• Species: Homo sapiens
• Alignment Length: 201
• Identity: 56/201 - (27%)
• Similarity: 85/201 - (42%)
• Gaps: 18/201 - (8%)

  Fly     7 RVAVVTGASSGIGAAVA---RHLVSAGVIVVGLARRVDRMKAIKEQLPPELQGRLHAIHCDVEDL 68
            |..:::|.|||||..:|   .|.......||...|.:.:.:.::......|...|.....||...
Human     6 RTVLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQTLTVAQLDVCSD 70

  Fly    69 DSVTAAFDWIEEQLGGCDILVNNAGCLNPGQLLTLELEQLQQVLNVNLMGVVICTRRAFRSMQQR 133
            :||......|:   |..|:||||||....|.|..|.|..:|.|.:.|..|.|...:.....|::|
Human    71 ESVAQCLSCIQ---GEVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFGAVRLVKAVLPGMKRR 132

  Fly   134 EVDGHVILINSLTGRN--IINPPGDELQVLNMYPLTKHGVTAMLEVLRQELRGFKTKIKVTSITP 196
            . .||:::|:|:.|..  |.|         ::|..:|..:....|.|..:|..|...|.:....|
Human   133 R-QGHIVVISSVMGLQGVIFN---------DVYAASKFALEGFFESLAIQLLQFNIFISLVEPGP 187

  Fly   197 GVTDTE 202
            .||:.|
Human   188 VVTEFE 193

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG40486	NP_001036311.2	YdfG	1..247	CDD:226674	56/201 (28%)
		NADB_Rossmann	1..242	CDD:304358	56/201 (28%)
RDH8	NP_056540.3	type1_17beta-HSD-like_SDR_c	6..262	CDD:187666	56/201 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1205
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900