Protein Alignment CG40486 and HSD11B1

DIOPT Version :9

• Sequence 1: NP_001036311.2
• Gene: CG40486 / 3355162
• FlyBaseID: FBgn0263830
• Length: 247
• Species: Drosophila melanogaster
• Sequence 2: NP_001193670.1
• Gene: HSD11B1 / 3290
• HGNCID: 5208
• Length: 292
• Species: Homo sapiens
• Alignment Length: 232
• Identity: 52/232 - (22%)
• Similarity: 99/232 - (42%)
• Gaps: 27/232 - (11%)

  Fly     2 ERWHDRVAVVTGASSGIGAAVARHLVSAGVIVVGLARRVDRMKAIKEQLPPELQGRLHAIHCDVE 66
            |....:..:|||||.|||..:|.||...|..||..||..:.::.:............|.|...:|
Human    30 EMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTME 94

  Fly    67 DLDSVTAAFDWIEEQ---LGGCDILVNNAGCLNPGQLLTLELEQLQQVLNVNLMGVVICTRRAFR 128
            |:   |.|..::.:.   :||.|:|:.|........|...::..:::.:.||.:..|:.|..|..
Human    95 DM---TFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALP 156

  Fly   129 SMQQREVDGHVILINSLTGRNIINPPGDELQVLNMYPLTKHGVTAMLEVLRQELRGFKTKIKVTS 193
            .::|.  :|.:::::||.|: :..|      ::..|..:|..:......:|:|....:..:.:|.
Human   157 MLKQS--NGSIVVVSSLAGK-VAYP------MVAAYSASKFALDGFFSSIRKEYSVSRVNVSITL 212

  Fly   194 ITPGVTDTEILPSGYGILPMLKPDDIAAGIMYVLGTP 230
            ...|:.|||.....            .:||:::...|
Human   213 CVLGLIDTETAMKA------------VSGIVHMQAAP 237

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG40486	NP_001036311.2	YdfG	1..247	CDD:226674	52/232 (22%)
		NADB_Rossmann	1..242	CDD:304358	52/232 (22%)
HSD11B1	NP_001193670.1	11beta-HSD1_like_SDR_c	32..279	CDD:187593	51/230 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1205
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900