DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG40486 and DHRS7C

DIOPT Version :9

Sequence 1:NP_001036311.2 Gene:CG40486 / 3355162 FlyBaseID:FBgn0263830 Length:247 Species:Drosophila melanogaster
Sequence 2:NP_001207422.1 Gene:DHRS7C / 201140 HGNCID:32423 Length:312 Species:Homo sapiens


Alignment Length:206 Identity:51/206 - (24%)
Similarity:91/206 - (44%) Gaps:35/206 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 DRVAVVTGASSGIGAAVARHLVSAGVIVVGLARRVDRMKAI-----------KEQLPPELQGRLH 59
            ::|.|:|.|.||:|...||...:.|..:|...:..:|::.:           |:...|:|     
Human    37 NKVVVITDAISGLGKECARVFHTGGARLVLCGKNWERLENLYDALISVADPSKQTFTPKL----- 96

  Fly    60 AIHCDVEDLDSVTAAFDWIEEQLG--GC-DILVNNAG--CLNPGQLLTLELEQLQQVLNVNLMGV 119
             :..|:.|:..|.   |..:|.|.  || |||:|||.  ...|...::|||:  :::::.|..|.
Human    97 -VLLDLSDISCVP---DVAKEVLDCYGCVDILINNASVKVKGPAHKISLELD--KKIMDANYFGP 155

  Fly   120 VICTRRAFRSMQQREVDGHVILINSLTGRNIINPPGDELQVLNMYPLTKHGVTAMLEVLRQELRG 184
            :..|:....:|..|.. |.::|:|::.|:       ..:.....|..:||......:.||.|:..
Human   156 ITLTKALLPNMISRRT-GQIVLVNNIQGK-------FGIPFRTTYAASKHAALGFFDCLRAEVEE 212

  Fly   185 FKTKIKVTSIT 195
            :...|...|.|
Human   213 YDVVISTVSPT 223

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG40486NP_001036311.2 YdfG 1..247 CDD:226674 51/206 (25%)
NADB_Rossmann 1..242 CDD:304358 51/206 (25%)
DHRS7CNP_001207422.1 11beta-HSD1_like_SDR_c 35..297 CDD:187593 51/206 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1205
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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