Protein Alignment CG40486 and Hsd11b1

DIOPT Version :10

• Sequence 1: NP_001036311.2
• Gene: CG40486 / 3355162
• FlyBaseID: FBgn0263830
• Length: 247
• Species: Drosophila melanogaster
• Sequence 2: XP_006497291.1
• Gene: Hsd11b1 / 15483
• MGIID: 103562
• Length: 304
• Species: Mus musculus
• Alignment Length: 204
• Identity: 53/204 - (25%)
• Similarity: 93/204 - (45%)
• Gaps: 15/204 - (7%)

  Fly     2 ERWHDRVAVVTGASSGIGAAVARHLVSAGVIVVGLARRVDRMKAIKEQLPPELQGRLHAIHCDVE 66
            |....:..:|||||.|||..:|.||...|..||..||..:.::.:..:.........|.|...:|
Mouse    42 EMLQGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLELGAASAHYIAGTME 106

  Fly    67 DLDSVTAAFDWIEEQ---LGGCDILVNNAGCLNPGQLLTLELEQLQQVLNVNLMGVVICTRRAFR 128
            |:   |.|..:|.:.   :||.|:|:.|........|...::..:::|:.||.:..|:.:..|..
Mouse   107 DM---TFAEQFIVKAGKLMGGLDMLILNHITQTSLSLFHDDIHSVRRVMEVNFLSYVVMSTAALP 168

  Fly   129 SMQQREVDGHVILINSLTGRNIINPPGDELQVLNMYPLTKHGVTAMLEVLRQELRGFKTKIKVTS 193
            .::|.  :|.:.:|:||.|:  :..|     ::..|..:|..:......:|.||...|..:.:|.
Mouse   169 MLKQS--NGSIAVISSLAGK--MTQP-----MIAPYSASKFALDGFFSTIRTELYITKVNVSITL 224

  Fly   194 ITPGVTDTE 202
            ...|:.|||
Mouse   225 CVLGLIDTE 233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG40486	NP_001036311.2	Rossmann-fold NAD(P)(+)-binding proteins	1..242	CDD:473865	53/204 (26%)
Hsd11b1	XP_006497291.1	11beta-HSD1_like_SDR_c	44..291	CDD:187593	52/202 (26%)