DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG40486 and XB1000829

DIOPT Version :9

Sequence 1:	NP_001036311.2	Gene:	CG40486 / 3355162	FlyBaseID:	FBgn0263830	Length:	247	Species:	Drosophila melanogaster
Sequence 2:	NP_001096251.1	Gene:	XB1000829 / 100124812	XenbaseID:	XB-GENE-1000830	Length:	323	Species:	Xenopus tropicalis

Alignment Length:	205	Identity:	52/205 - (25%)
Similarity:	96/205 - (46%)	Gaps:	27/205 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 RVAVVTGASSGIGAAVARHLV-------SAGVIVVGLARRVDRMKAIKEQLPPELQGRLHAIHCD 64
            :..::||.|||||.|:|..|.       .....:..||::.|.:.|.:..|...::.:...:.|:
Frog     4 KTVLITGCSSGIGLAIATKLARDEQKRFKVYATMRNLAKQDDLIAATEGYLGKTMEIKEMDVCCE 68

  Fly    65 VEDLDSVTAAFDWIEEQLGGCDILVNNAGCLNPGQLLTLELEQLQQVLNVNLMGVVICTRRAFRS 129
                ||:......|.::  ..||||:|||....|.:....:|:::.|::.|..|:|...:.....
Frog    69 ----DSIRNCVSSIPDR--HIDILVSNAGVGLIGPIECQTIEEMKTVMDTNFFGLVRLLKETLPD 127

  Fly   130 MQQREVDGHVILINSLTGRN--IINPPGDELQVLNMYPLTKHGVTAMLEVLRQELRGFKTKIKVT 192
            |::|: .||:::|:|:.|..  :.|         ::|..:|..|....|.|  .::..|.|:.::
Frog   128 MKRRK-SGHIVIISSVMGIQGILFN---------DVYAASKFAVEGFCESL--AIQALKFKLHLS 180

  Fly   193 SITPGVTDTE 202
            .|.||...||
Frog   181 LIEPGPVVTE 190

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG40486	NP_001036311.2	YdfG	1..247	CDD:226674	52/205 (25%)
CG40486	NP_001036311.2	NADB_Rossmann	1..242	CDD:304358	52/205 (25%)
XB1000829	NP_001096251.1	type1_17beta-HSD-like_SDR_c	4..261	CDD:187666	52/205 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910