DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG42346 and AT3G47570

DIOPT Version :9

Sequence 1:	NP_001036303.2	Gene:	CG42346 / 3355160	FlyBaseID:	FBgn0259677	Length:	1817	Species:	Drosophila melanogaster
Sequence 2:	NP_566892.1	Gene:	AT3G47570 / 823911	AraportID:	AT3G47570	Length:	1010	Species:	Arabidopsis thaliana

Alignment Length:	1025	Identity:	207/1025 - (20%)
Similarity:	360/1025 - (35%)	Gaps:	281/1025 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   302 IRHLQFSHSHLEALKDNSLRNVRSSLESLSIVNGKLTQMPSRALSSMQKLTALDFDYNEIVRVDD 366
            :.||:.....|..:...|:.|: |.|.||.:..........:.:..:.:|..||...|.:.....
plant    68 VTHLELGRLQLGGVISPSIGNL-SFLVSLDLYENFFGGTIPQEVGQLSRLEYLDMGINYLRGPIP 131

  Fly   367 YSFYGL-RISKLNMKGNRLQGMPEHAFAGLEECMQEIDVSENGLRTFPLMALRKLDHLRILRLSN 430
            ...|.. |:..|.:..|||.|........|...:| :::..|.:|.....:|..|..|..|.||:
plant   132 LGLYNCSRLLNLRLDSNRLGGSVPSELGSLTNLVQ-LNLYGNNMRGKLPTSLGNLTLLEQLALSH 195

  Fly   431 NRIPTFYGDIQLATNNASAAAAAVGAFQLPSLIFLDLSSNQFAEIGPDCFRAFPQLKTLSFYANQ 495
            |.:.   |:|      .|..|      ||..:..|.|.:|.|:.:.|........||.|....|.
plant   196 NNLE---GEI------PSDVA------QLTQIWSLQLVANNFSGVFPPALYNLSSLKLLGIGYNH 245

  Fly   496 IE-LVQPEAFKSLRELMSLDMSHNRIIGLDPKVFEKNKRLQTVDLSHNHIHTIGGVFSNLPQLRE 559
            .. .::|:....|..|:|.:|..|...|..|........|:.:.::.|::......|.|:|.|:.
plant   246 FSGRLRPDLGILLPNLLSFNMGGNYFTGSIPTTLSNISTLERLGMNENNLTGSIPTFGNVPNLKL 310

  Fly   560 VFLSENNI-------LELPADAFTNSTNVDVIYLESNAIAHIDPNVFSTLVNLDHLYLRSNFIPL 617
            :||..|::       ||. ..:.||.|.::.:.:..|.:...
plant   311 LFLHTNSLGSDSSRDLEF-LTSLTNCTQLETLGIGRNRLGGD----------------------- 351

  Fly   618 LPVTLFDKSTKLTSLSLDNNEIQ---DLEIGMFRKLEHLREVRLHNNRIRRVRRGVFEPLPSLQE 679
            ||:::.:.|.||.:|.|....|.   ..:||                           .|.:||:
plant   352 LPISIANLSAKLVTLDLGGTLISGSIPYDIG---------------------------NLINLQK 389

  Fly   680 LHIQKNSIEDIEPQAFHTLENMQHINLQDNQLTVLEDIFPDENSSLLSVQLEANYLHKVHPRTFS 744
            |.:.:|.:....|.:...|.|:::::|..|:|:.....|....:.|.::.|..|....:.|.:..
plant   390 LILDQNMLSGPLPTSLGKLLNLRYLSLFSNRLSGGIPAFIGNMTMLETLDLSNNGFEGIVPTSLG 454

  Fly   745 RQQKVQIMWLKDN--------------QLTRVE---RSFFADTPQ-------LGRLYLSDNKIRD 785
            ....:..:|:.||              ||.|::   .|.....||       ||.|.|.|||:..
plant   455 NCSHLLELWIGDNKLNGTIPLEIMKIQQLLRLDMSGNSLIGSLPQDIGALQNLGTLSLGDNKLSG 519

  Fly   786 IEKDTFVNLLLLQFLDLSGNQLRQLRRDYFAPLQDL------EELSLARNHIEAIEGYAFAKLKN 844
            ....|..|.|.::.|.|.||.       ::..:.||      :|:.|:.|.:.......||....
plant   520 KLPQTLGNCLTMESLFLEGNL-------FYGDIPDLKGLVGVKEVDLSNNDLSGSIPEYFASFSK 577

  Fly   845 LKSLDLSHNPLVQL--TRDIFSNEFPLNSLNLGNCSL-----------------RKLEQHAFK-- 888
            |:.|:||.|.|...  .:.||.|...::.  :||..|                 ..:::|:.:
plant   578 LEYLNLSFNNLEGKVPVKGIFENATTVSI--VGNNDLCGGIMGFQLKPCLSQAPSVVKKHSSRLK 640

  Fly   889 -------------------SLTNL----NELNLERNQLNPADIQTL-------DIPNLRRLLLSH 923
                               |:|.:    .:.|.|.|...|:.::.|       |:.|      :.
plant   641 KVVIGVSVGITLLLLLFMASVTLIWLRKRKKNKETNNPTPSTLEVLHEKISYGDLRN------AT 699

  Fly   924 NNFSYAGSVG------IMAGML--------DRLRSLQQLSMSNCSLGQIPDLLFAKNTNLVRLDL 974
            |.||.:..||      :...:|        .::.::|:.......:.:...|...::.|||:|
plant   700 NGFSSSNMVGSGSFGTVYKALLLTEKKVVAVKVLNMQRRGAMKSFMAECESLKDIRHRNLVKL-- 762

  Fly   975 CDNRLTQINRNIFSGLNVFK------------ELRLCRNELSDFPHIALYNLSTLESLDLARNQL 1027
                ||..:...|.| |.|:            ::.|...|:.:. |.....|:.||.|::|.:..
plant   763 ----LTACSSIDFQG-NEFRALIYEFMPNGSLDMWLHPEEVEEI-HRPSRTLTLLERLNIAIDVA 821

  Fly  1028 ASIDFFKLS-----GTLNLR-QLILRDNKITA-LSGFNAVNL----------TQLDSVDLSGN-- 1073
            :.:|:..:.     ...:|: ..:|.|:.:|| :|.|....|          .||.|..:.|.
plant   822 SVLDYLHVHCHEPIAHCDLKPSNVLLDDDLTAHVSDFGLARLLLKFDEESFFNQLSSAGVRGTIG 886

  Fly  1074 -----------------------LLLSL-----PANFL---RHSINLQKVHLSNNRFLQIPSSAL 1107
                                   |||.:     |.|.|   ..::|.........|.|.|...::
plant   887 YAAPEYGVGGQPSINGDVYSFGILLLEMFTGKRPTNELFGGNFTLNSYTKSALPERILDIVDESI 951

  Fly  1108 SDVSI----PRLSWLNLT---------GNPINRIYT---VKE-----ERY 1136
            ..:.:    |.:..|.:.         .:|:||:.|   |||     ||:
plant   952 LHIGLRVGFPVVECLTMVFEVGLRCCEESPMNRLATSIVVKELISIRERF 1001

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42346	NP_001036303.2	leucine-rich repeat	303..325	CDD:275380	5/21 (24%)
		LRR_8	325..384	CDD:290566	12/59 (20%)
		leucine-rich repeat	327..350	CDD:275380	3/22 (14%)
		leucine-rich repeat	351..461	CDD:275380	28/110 (25%)
		LRR_8	373..433	CDD:290566	17/59 (29%)
		LRR_RI	397..648	CDD:238064	58/261 (22%)
		leucine-rich repeat	399..422	CDD:275380	5/22 (23%)
		leucine-rich repeat	462..485	CDD:275380	5/22 (23%)
		LRR_8	465..520	CDD:290566	15/55 (27%)
		leucine-rich repeat	486..509	CDD:275380	6/23 (26%)
		LRR_8	508..567	CDD:290566	15/58 (26%)
		leucine-rich repeat	510..533	CDD:275380	6/22 (27%)
		LRR_RI	527..785	CDD:238064	57/291 (20%)
		leucine-rich repeat	534..556	CDD:275380	4/21 (19%)
		LRR_8	555..613	CDD:290566	11/64 (17%)
		leucine-rich repeat	557..580	CDD:275380	8/29 (28%)
		leucine-rich repeat	581..604	CDD:275380	1/22 (5%)
		LRR_8	604..663	CDD:290566	10/61 (16%)
		leucine-rich repeat	605..628	CDD:275380	3/22 (14%)
		leucine-rich repeat	629..652	CDD:275380	6/25 (24%)
		LRR_8	652..711	CDD:290566	10/58 (17%)
		leucine-rich repeat	653..676	CDD:275380	1/22 (5%)
		leucine-rich repeat	677..700	CDD:275380	6/22 (27%)
		leucine-rich repeat	701..748	CDD:275380	8/46 (17%)
		leucine-rich repeat	725..736	CDD:275378	3/10 (30%)
		leucine-rich repeat	749..772	CDD:275380	7/39 (18%)
		LRR_8	771..831	CDD:290566	21/72 (29%)
		leucine-rich repeat	773..793	CDD:275380	8/19 (42%)
		LRR_RI	804..1076	CDD:238064	71/396 (18%)
		LRR_8	821..903	CDD:290566	24/131 (18%)
		leucine-rich repeat	821..844	CDD:275380	6/28 (21%)
		leucine-rich repeat	845..868	CDD:275380	9/24 (38%)
		leucine-rich repeat	869..892	CDD:275380	5/60 (8%)
		leucine-rich repeat	893..915	CDD:275380	6/32 (19%)
		leucine-rich repeat	916..944	CDD:275380	6/41 (15%)
		leucine-rich repeat	945..968	CDD:275380	2/22 (9%)
		LRR_8	967..1027	CDD:290566	18/71 (25%)
		leucine-rich repeat	969..992	CDD:275380	7/22 (32%)
		leucine-rich repeat	993..1014	CDD:275380	4/32 (13%)
		LRR_8	1015..1075	CDD:290566	17/101 (17%)
		leucine-rich repeat	1017..1040	CDD:275380	5/27 (19%)
		leucine-rich repeat	1041..1064	CDD:275380	8/34 (24%)
		LRR_RI	<1047..1244	CDD:238064	31/155 (20%)
		LRR_8	1063..1125	CDD:290566	16/107 (15%)
		leucine-rich repeat	1089..1114	CDD:275380	3/28 (11%)
		leucine-rich repeat	1115..1162	CDD:275380	10/39 (26%)
		LRR_8	1163..1219	CDD:290566
		leucine-rich repeat	1163..1186	CDD:275380
		leucine-rich repeat	1187..1210	CDD:275380
		leucine-rich repeat	1211..1233	CDD:275380
		leucine-rich repeat	1234..1257	CDD:275380
		LRR_8	1235..1292	CDD:290566
		leucine-rich repeat	1258..1279	CDD:275380
		leucine-rich repeat	1282..1306	CDD:275380
AT3G47570	NP_566892.1	PLN00113	29..996	CDD:215061	205/1018 (20%)
		leucine-rich repeat	68..91	CDD:275380	5/23 (22%)
		leucine-rich repeat	92..115	CDD:275380	3/22 (14%)
		leucine-rich repeat	116..139	CDD:275380	5/22 (23%)
		leucine-rich repeat	140..163	CDD:275380	6/22 (27%)
		leucine-rich repeat	164..187	CDD:275380	5/23 (22%)
		leucine-rich repeat	214..235	CDD:275380	5/20 (25%)
		leucine-rich repeat	236..260	CDD:275380	6/23 (26%)
		leucine-rich repeat	261..284	CDD:275380	6/22 (27%)
		leucine-rich repeat	285..307	CDD:275380	4/21 (19%)
		leucine-rich repeat	308..337	CDD:275380	8/29 (28%)
		leucine-rich repeat	338..362	CDD:275380	4/46 (9%)
		leucine-rich repeat	363..386	CDD:275380	7/49 (14%)
		leucine-rich repeat	387..410	CDD:275380	6/22 (27%)
		leucine-rich repeat	411..434	CDD:275380	4/22 (18%)
		leucine-rich repeat	435..458	CDD:275380	4/22 (18%)
		leucine-rich repeat	459..482	CDD:275380	3/22 (14%)
		leucine-rich repeat	483..506	CDD:275380	5/22 (23%)
		leucine-rich repeat	507..553	CDD:275380	16/52 (31%)
		leucine-rich repeat	554..577	CDD:275380	5/22 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	146	1.000	Inparanoid score	I1746
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050