DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42346 and AT2G24130

DIOPT Version :9

Sequence 1:	NP_001036303.2	Gene:	CG42346 / 3355160	FlyBaseID:	FBgn0259677	Length:	1817	Species:	Drosophila melanogaster
Sequence 2:	NP_001324448.1	Gene:	AT2G24130 / 816947	AraportID:	AT2G24130	Length:	995	Species:	Arabidopsis thaliana

Alignment Length:	1154	Identity:	257/1154 - (22%)
Similarity:	408/1154 - (35%)	Gaps:	377/1154 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   314 ALKDNSLRNVRSSLESLSIVNGKLTQMPSRALSSMQKLTALDFDYNEIVRVDDYSFYGLRISKLN 378
            |.|:|....::|...||......:...|..:|||.  :::.....:.:|.|.::|  |::.:|
plant    20 ASKENDHELIKSDQISLLSFKSSIVSDPQNSLSSW--ISSSSSSSSMLVDVCNWS--GVKCNK-- 78

  Fly   379 MKGNRLQGMPEHAFAGLEECMQ--EIDVSENGLRTFPLMALRKLDHLRILRLSNNRIPTFYGDIQ 441
                              |..|  |:|:|...|.                           |:|.
plant    79 ------------------ESTQVIELDISGRDLG---------------------------GEIS 98

  Fly   442 LATNNASAAAAAVGAFQLPSLIFLDLSSNQF-AEIGPDCFRAFPQLKTLSFYANQIELVQPEAFK 505
            .:..|            |..|..||||.|.| .:|.|:.......||.||...|.:....|:...
plant    99 PSIAN------------LTGLTVLDLSRNFFVGKIPPEIGSLHETLKQLSLSENLLHGNIPQELG 151

  Fly   506 SLRELMSLDMSHNRIIGLDP-KVF--EKNKRLQTVDLSHN----------HIHTIGGVFSNLPQL 557
            .|..|:.||:..||:.|..| ::|  ..:..||.:|||:|          |.|        |.:|
plant   152 LLNRLVYLDLGSNRLNGSIPVQLFCNGSSSSLQYIDLSNNSLTGEIPLNYHCH--------LKEL 208

  Fly   558 REVFLSENNILELPADAFTNSTNVDVIYLESNAIA-HIDPNVFSTLVNLDHLYLRSN-FIPLLPV 620
            |.:.|..|.:......:.:||||:..:.||||.:: .:...|.|.:..|..|||..| |:.
plant   209 RFLLLWSNKLTGTVPSSLSNSTNLKWMDLESNMLSGELPSQVISKMPQLQFLYLSYNHFVS---- 269

  Fly   621 TLFDKSTKLTSLSLDNNEIQDLEIGMFRKLEHLREVRLHNNRIRRVRRGVFEPL-------PSLQ 678
                                                  |||...      .||.       ..||
plant   270 --------------------------------------HNNNTN------LEPFFASLANSSDLQ 290

  Fly   679 ELHIQKNSI-EDIEPQAFHTLENMQHINLQDNQLTVLEDIFPDENSSLLS---VQLEANYLHKVH 739
            ||.:..||: .:|.....|...|:..|:|..|:   :....|.|.|:||:   :.|.:|.|....
plant   291 ELELAGNSLGGEITSSVRHLSVNLVQIHLDQNR---IHGSIPPEISNLLNLTLLNLSSNLLSGPI 352

  Fly   740 PRTFSRQQKVQIMWLKDNQLTRVERSFFADTPQLGRLYLSDNKIRDIEKDTFVNLLLLQFLDLSG 804
            ||...:..|::.::|.:|.||........|.|:||.|.:|.|.:.....|:|.|
plant   353 PRELCKLSKLERVYLSNNHLTGEIPMELGDIPRLGLLDVSRNNLSGSIPDSFGN----------- 406

  Fly   805 NQLRQLRRDYFAPLQDLEELSLARNHIEAIEGYAFAKLKNLKSLDLSHNPLV-QLTRDIFSNEFP 868
              |.||||           |.|..||:......:..|..||:.||||||.|. .:..::.||
plant   407 --LSQLRR-----------LLLYGNHLSGTVPQSLGKCINLEILDLSHNNLTGTIPVEVVSN--- 455

  Fly   869 LNSLNLGNCSLRKLEQHAFKSLTNLNELNLERNQLN---PADIQTLDI----------------P 914
                      ||.|:.:          |||..|.|:   |.::..:|:                |
plant   456 ----------LRNLKLY----------LNLSSNHLSGPIPLELSKMDMVLSVDLSSNELSGKIPP 500

  Fly   915 NLRR-LLLSHNNFSYAGSVGIMAGMLDRLRSLQQLSMS-NCSLGQIPDLLFAKNTNLVRLDLCDN 977
            .|.. :.|.|.|.|..|....:...|.:|..|::|.:| |...|.||. .|.:::.|..|:...|
plant   501 QLGSCIALEHLNLSRNGFSSTLPSSLGQLPYLKELDVSFNRLTGAIPP-SFQQSSTLKHLNFSFN 564

  Fly   978 RLT--QINRNIFSGLNV------------FKELRLCRNELSDFPHIALYNLSTLESLDLARNQLA 1028
            .|:  ..::..||.|.:            .|.::.|:.: ..:|.:.|..|.:|    :|...|.
plant   565 LLSGNVSDKGSFSKLTIESFLGDSLLCGSIKGMQACKKK-HKYPSVLLPVLLSL----IATPVLC 624

  Fly  1029 SIDF-------FKLSGTLNLRQLILRDNK----------------ITALSGFNAVNLTQLDSVDL 1070
            ...:       |..:.|:..::.:..:.|                |.|..||||.:|..
plant   625 VFGYPLVQRSRFGKNLTVYAKEEVEDEEKQNQNDPKYPRISYQQLIAATGGFNASSLIG------ 683

  Fly  1071 SGNLLLSLPANFLRHSINLQKVHLSNNRFLQI----PSSALSDVSIPRLSWLNLTGNPINRIYTV 1131
            ||..            .::.|..|.||..:.:    |.:|           |..:|:.......:
plant   684 SGRF------------GHVYKGVLRNNTKVAVKVLDPKTA-----------LEFSGSFKRECQIL 725

  Fly  1132 KEERYPYLKELYICQTNLSILTSKDFEAFQALQHLHLVNNRITR-ISPGAFKSLTNLLTLDLSVN 1195
            |..|:..|         :.|:|:.....|.||....:.|..:.| :.||.:.|      .:|.:.
plant   726 KRTRHRNL---------IRIITTCSKPGFNALVLPLMPNGSLERHLYPGEYSS------KNLDLI 775

  Fly  1196 ELEMLPKERLQGLRLLRF---LNISH------NTLKDLE------EFSVDLL-----EMQTLD-- 1238
            :|..:..:..:|:..|..   :.:.|      |.|.|.|      :|.:..|     |..:.|
plant   776 QLVNICSDVAEGIAYLHHYSPVKVVHCDLKPSNILLDDEMTALVTDFGISRLVQGVEETVSTDDS 840

  Fly  1239 LSFNQLDRI--------------SKKTFRNLHG--------LLELFLMGNRMT-VLSNDAFRFLR 1280
            :||...|.:              .|:.  :.||        |||: :.|.|.| ||.|:.    .
plant   841 VSFGSTDGLLCGSVGYIAPEYGMGKRA--STHGDVYSFGVLLLEI-VSGRRPTDVLVNEG----S 898

  Fly  1281 KLHVLDLRKNYFELVP--LEPLRPLETNLRTLRLEENPLHCSCDAQKLW 1327
            .||  :..|:::   |  ||.:  :|..|...:.:..|..|    :|||
plant   899 SLH--EFMKSHY---PDSLEGI--IEQALSRWKPQGKPEKC----EKLW 936

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42346	NP_001036303.2	leucine-rich repeat	303..325	CDD:275380	3/10 (30%)
		LRR_8	325..384	CDD:290566	12/58 (21%)
		leucine-rich repeat	327..350	CDD:275380	6/22 (27%)
		leucine-rich repeat	351..461	CDD:275380	15/111 (14%)
		LRR_8	373..433	CDD:290566	7/61 (11%)
		LRR_RI	397..648	CDD:238064	63/268 (24%)
		leucine-rich repeat	399..422	CDD:275380	5/24 (21%)
		leucine-rich repeat	462..485	CDD:275380	9/23 (39%)
		LRR_8	465..520	CDD:290566	19/55 (35%)
		leucine-rich repeat	486..509	CDD:275380	7/22 (32%)
		LRR_8	508..567	CDD:290566	21/71 (30%)
		leucine-rich repeat	510..533	CDD:275380	8/25 (32%)
		LRR_RI	527..785	CDD:238064	69/282 (24%)
		leucine-rich repeat	534..556	CDD:275380	9/31 (29%)
		LRR_8	555..613	CDD:290566	18/58 (31%)
		leucine-rich repeat	557..580	CDD:275380	6/22 (27%)
		leucine-rich repeat	581..604	CDD:275380	6/23 (26%)
		LRR_8	604..663	CDD:290566	9/59 (15%)
		leucine-rich repeat	605..628	CDD:275380	6/23 (26%)
		leucine-rich repeat	629..652	CDD:275380	0/22 (0%)
		LRR_8	652..711	CDD:290566	17/66 (26%)
		leucine-rich repeat	653..676	CDD:275380	5/29 (17%)
		leucine-rich repeat	677..700	CDD:275380	8/23 (35%)
		leucine-rich repeat	701..748	CDD:275380	13/49 (27%)
		leucine-rich repeat	725..736	CDD:275378	4/13 (31%)
		leucine-rich repeat	749..772	CDD:275380	5/22 (23%)
		LRR_8	771..831	CDD:290566	17/59 (29%)
		leucine-rich repeat	773..793	CDD:275380	7/19 (37%)
		LRR_RI	804..1076	CDD:238064	75/330 (23%)
		LRR_8	821..903	CDD:290566	23/82 (28%)
		leucine-rich repeat	821..844	CDD:275380	5/22 (23%)
		leucine-rich repeat	845..868	CDD:275380	10/23 (43%)
		leucine-rich repeat	869..892	CDD:275380	3/22 (14%)
		leucine-rich repeat	893..915	CDD:275380	7/40 (18%)
		leucine-rich repeat	916..944	CDD:275380	8/28 (29%)
		leucine-rich repeat	945..968	CDD:275380	8/23 (35%)
		LRR_8	967..1027	CDD:290566	14/73 (19%)
		leucine-rich repeat	969..992	CDD:275380	7/24 (29%)
		leucine-rich repeat	993..1014	CDD:275380	4/20 (20%)
		LRR_8	1015..1075	CDD:290566	15/82 (18%)
		leucine-rich repeat	1017..1040	CDD:275380	5/29 (17%)
		leucine-rich repeat	1041..1064	CDD:275380	8/38 (21%)
		LRR_RI	<1047..1244	CDD:238064	46/239 (19%)
		LRR_8	1063..1125	CDD:290566	10/65 (15%)
		leucine-rich repeat	1089..1114	CDD:275380	6/28 (21%)
		leucine-rich repeat	1115..1162	CDD:275380	8/46 (17%)
		LRR_8	1163..1219	CDD:290566	11/65 (17%)
		leucine-rich repeat	1163..1186	CDD:275380	6/23 (26%)
		leucine-rich repeat	1187..1210	CDD:275380	3/22 (14%)
		leucine-rich repeat	1211..1233	CDD:275380	8/41 (20%)
		leucine-rich repeat	1234..1257	CDD:275380	5/38 (13%)
		LRR_8	1235..1292	CDD:290566	19/81 (23%)
		leucine-rich repeat	1258..1279	CDD:275380	9/21 (43%)
		leucine-rich repeat	1282..1306	CDD:275380	7/25 (28%)
AT2G24130	NP_001324448.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	146	1.000	Inparanoid score	I1746
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050