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Protein Alignment CG42346 and Igfals

DIOPT Version :10

Sequence 1:	NP_001036303.2	Gene:	CG42346 / 3355160	FlyBaseID:	FBgn0259677	Length:	1817	Species:	Drosophila melanogaster
Sequence 2:	NP_445781.3	Gene:	Igfals / 79438	RGDID:	68429	Length:	603	Species:	Rattus norvegicus

Alignment Length:	584	Identity:	164/584 - (28%)
Similarity:	253/584 - (43%)	Gaps:	96/584 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   558 REVFLSENNILELPADAFTNSTNVDVIYLESNAIAHIDPNVFSTLVNLDHLYLRSNFIPLLPVTL 622
            |.::|..||:..:|:.||.|.:::|.:.|:.:.:..::|.....|.||.||:|..|.:..|.|.|
  Rat    77 RALWLDGNNLSSIPSAAFQNLSSLDFLNLQGSWLRSLEPQALLGLQNLYHLHLERNRLRNLAVGL 141

  Fly   623 FDKSTKLTSLSLDNNEIQDLEIGMFRKLEHLREVRLHNNRIRRVRRGVFEPLPSLQELHIQKNSI 687
            |..:..|.||||.:|.:..||.|:|:.|.||.::.|..|.:..:...||:.|.:|.||.:..|.:
  Rat   142 FTHTPSLASLSLSSNLLGRLEEGLFQGLSHLWDLNLGWNSLVVLPDTVFQGLGNLHELVLAGNKL 206

  Fly   688 EDIEPQAFHTLENMQHINLQDNQL-TVLEDIFPDENSSLLSVQLEANYLHKVH-PRTFSRQQKVQ 750
            ..::|..|..|..::.::|..|.| :|..::|                   || ||       :|
  Rat   207 TYLQPALFCGLGELRELDLSRNALRSVKANVF-------------------VHLPR-------LQ 245

  Fly   751 IMWLKDNQLTRVERSFFADTPQLGRLYLSDNKIRDIEKDTFVNLLLLQFLDLSGNQLRQLRRDYF 815
            .::|..|.:|.|....|.....|..|.||.|::..:.:|||..||.|..|.|:.|.:..||...|
  Rat   246 KLYLDRNLITAVAPRAFLGMKALRWLDLSHNRVAGLMEDTFPGLLGLHVLRLAHNAIASLRPRTF 310

  Fly   816 APLQDLEELSLARNHIEAIEGYAFAKLKNLKSLDLSHNPLVQLTRDIFSNEFPLNSLNL-GNCSL 879
            ..|..||||.|..|.|..:....|..|..|:.|.|:.|.:.::....||..|.:..:|| ||| |
  Rat   311 KDLHFLEELQLGHNRIRQLGERTFEGLGQLEVLTLNDNQITEVRVGAFSGLFNVAVMNLSGNC-L 374

  Fly   880 RKLEQHAFKSLTNLNELNLERNQLNPADIQTL-DIPNLRRLLLSHNNFSYAGSVGIMAGMLDRLR 943
            |.|.:..|:.|..|:.|:||.:.|....:.|. .:..||||.|..|:.|
  Rat   375 RSLPERVFQGLDKLHSLHLEHSCLGHVRLHTFAGLSGLRRLFLRDNSIS---------------- 423

  Fly   944 SLQQLSMSNCSLGQIPDLLFAKNTNLVRLDLCDNRLTQINRNIFSGLNVFKELRLCRNELSDFPH 1008
            |:::.|::..|             .|:.|||..||||.:.|.:|.||...:.|.|..|:|:....
  Rat   424 SIEEQSLAGLS-------------ELLELDLTTNRLTHLPRQLFQGLGHLEYLLLSYNQLTTLSA 475

  Fly  1009 IALYNLSTLESLDLARNQLASIDFFKLSGTLNLRQLILRDNKITALSGFNAVNLTQLDSVDLSGN 1073
            ..|..|.....||::.|.|.::.....|....||.|.||:|.:...|
  Rat   476 EVLGPLQRAFWLDISHNHLETLAEGLFSSLGRLRYLSLRNNSLQTFS------------------ 522

  Fly  1074 LLLSLPANFLRHSINLQKVHLSNNRF-LQIPSSALSDVS------IPRLSWLNLTGNPINRIYT 1130
                       ....|:::.|..|.: ...|..||.|.:      :||.......|:....:||
  Rat   523 -----------PQPGLERLWLDANPWDCSCPLKALRDFALQNPGVVPRFVQTVCEGDDCQPVYT 575

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.