DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG42346 and Lrrc15

DIOPT Version :9

Sequence 1:NP_001036303.2 Gene:CG42346 / 3355160 FlyBaseID:FBgn0259677 Length:1817 Species:Drosophila melanogaster
Sequence 2:NP_083249.1 Gene:Lrrc15 / 74488 MGIID:1921738 Length:579 Species:Mus musculus


Alignment Length:494 Identity:139/494 - (28%)
Similarity:226/494 - (45%) Gaps:72/494 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly   566 NILELPADAFTNSTNVDVIYLESNAIAHIDPNVFSTLVNLDHLYLRSNFIPLLPVTLFDKSTKLT 630
            :|.|||.|.|.|.:.:..:.:|.|.:|:|.|..|..|.:|.||.|.:|.:..|||.||.....|.
Mouse    64 HITELPEDKFLNISALIALKMEKNELANIMPGAFRNLGSLRHLSLANNKLKNLPVRLFQDVNNLE 128

  Fly   631 SLSLDNNEIQDLEIGMFRKLEHLREVRLHNNRIRRVRRGVFEPLPSLQELHIQKNSIEDIEPQAF 695
            :|.|.||::..::...|.:..:|:|::|:.|.:..:..|||:.|..|.:|::..|....:.|:.|
Mouse   129 TLLLSNNQLVQIQPAQFSQFSNLKELQLYGNNLEYIPEGVFDHLVGLTKLNLGNNGFTHLSPRVF 193

  Fly   696 HTLENMQHINLQDNQLTVLEDIFPDENSSLLSVQLEANYLHKVHPRTFSRQQKVQIMWLKDNQLT 760
            ..|.|:|.:.|.:|:|:                        .:...||.....:|.:.|::||:.
Mouse   194 QHLGNLQVLRLYENRLS------------------------DIPMGTFDALGNLQELALQENQIG 234

  Fly   761 RVERSFFADTPQLGRLYLSDNKIRDIEKDTFVNLLLLQFLDLSGNQLRQLRRDYFAPLQDLEELS 825
            .:....|.:...|.|||||:|.|..:....|:.|..|..|.|.||.|::|....|.|:.:|.||.
Mouse   235 TLSPGLFHNNRNLQRLYLSNNHISHLPPGIFMQLPHLNKLTLFGNSLKELSPGVFGPMPNLRELW 299

  Fly   826 LARNHIEAIEGYAFAKLKNLKSLDLSHNPLVQLTRDIFSNEFPLNSLNLGNCSLRKLEQHAFKSL 890
            |..|||.::...||:.|..|:.|.||||.|..::...|:....|..|:|...:|:.|:.:.|:||
Mouse   300 LYNNHITSLPDNAFSHLNQLQVLILSHNQLSYISPGAFNGLTNLRELSLHTNALQDLDGNVFRSL 364

  Fly   891 TNLNELNLERNQLN--PADIQTLDIPNLRRLLLSHNNFSYAGSVGIMAGMLDRLRSLQQLSMSN- 952
            .||..::|:.|:|.  |..| ..::..|..:.|.:||..     .:..|:.|.|.:|.:|.:.: 
Mouse   365 ANLRNVSLQNNRLRQLPGSI-FANVNGLMTIQLQNNNLE-----NLPLGIFDHLGNLCELRLYDN 423

  Fly   953 ---CSLGQIP--DLLFAKNTNL--VRLDLCDN-------RLTQINRNIFSGLNVFKELRLCRNEL 1003
               |....:|  |.|......|  ..|.:|.:       .|..||.| |.|.:|....   ..|:
Mouse   424 PWRCDSNILPLHDWLILNRARLGTDTLPVCSSPASVRGQSLVIINVN-FPGPSVQGPE---TPEV 484

  Fly  1004 SDFPHIALY---------------------NLSTLESLD 1021
            |.:|..:.|                     :|:|:|.:|
Mouse   485 SSYPDTSSYPDSTSISSTTEITRSTDDDYTDLNTIEPID 523

Known Domains:


Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.

GeneSequenceDomainRegion External IDIdentity
CG42346NP_001036303.2 leucine-rich repeat 303..325 CDD:275380
LRR_8 325..384 CDD:290566
leucine-rich repeat 327..350 CDD:275380
leucine-rich repeat 351..461 CDD:275380
LRR_8 373..433 CDD:290566
LRR_RI 397..648 CDD:238064 29/81 (36%)
leucine-rich repeat 399..422 CDD:275380
leucine-rich repeat 462..485 CDD:275380
LRR_8 465..520 CDD:290566
leucine-rich repeat 486..509 CDD:275380