DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG42346 and CG7800

DIOPT Version :9

Sequence 1:NP_001036303.2 Gene:CG42346 / 3355160 FlyBaseID:FBgn0259677 Length:1817 Species:Drosophila melanogaster
Sequence 2:NP_649770.1 Gene:CG7800 / 40963 FlyBaseID:FBgn0037552 Length:533 Species:Drosophila melanogaster


Alignment Length:718 Identity:155/718 - (21%)
Similarity:244/718 - (33%) Gaps:265/718 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   607 HLYLRSNFIPLLPVTLFD-KSTKLTSLSLDNNEIQDLEIGMFRKLEHLREVRLHNNRIRRVRRGV 670
            ||..||.       |..| |:||||...:|:.|                             :.|
  Fly    30 HLLGRSR-------TFSDKKATKLTEFHMDSCE-----------------------------KKV 58

  Fly   671 FEPLPSLQELHIQKNSIEDIEPQAFHTLENMQHINLQDNQLTVLEDIFPDENSSLLSVQLEANYL 735
            .:.:|:|:.|.::.....|.      |:.::       |||..           |.|:||....|
  Fly    59 LKLMPNLRTLELENCDSPDF------TMNDL-------NQLPY-----------LTSLQLRRGNL 99

  Fly   736 HKVHPRTFSRQQKVQIMWLKDNQLTRVERSFFADTPQLGRLYLSDNKIRDIEKDTFVNLLLLQFL 800
            ..:|...||:...::|:.|..|.:||:....|....||..|.|..|.|:.:..|.|.||..|..|
  Fly   100 LGLHDEHFSKWPNMKILMLGGNNITRLSNECFKGLAQLWLLSLPGNGIQGLPWDVFQNLPELLHL 164

  Fly   801 DLSGNQLRQLRRDYFAPLQDLEELSLARNHIEAIEGYAFAKLKNLKSLDLSHNPLVQLTRDIFSN 865
            |||||::..|..:.|..:..||.|.|..|.:..|...:...|.||:.||:|              
  Fly   165 DLSGNRIETLHENIFTGVPKLEMLLLNGNPLTWIAPTSLKSLSNLRLLDMS-------------- 215

  Fly   866 EFPLNSLNLGNCSLRKLEQHAFKSLTNLNELNLERNQLNPADIQTLDIPNLRRLLLSHNNFSYAG 930
                      ||                            ..:..|.:|....|:|.::      
  Fly   216 ----------NC----------------------------GPLPDLSLPGAHTLILDNS------ 236

  Fly   931 SVGIMAGMLDRLRSLQQLSMSNCSLGQI--PDLLFAKNTNLVRLDLCDNRLTQINRNIFSGLNVF 993
              |:.  .||.|.|:.:|......:.:|  ||     .::::.|||..|.||             
  Fly   237 --GVQ--RLDILGSVHKLQARKNHITEIKLPD-----KSSVIELDLHSNLLT------------- 279

  Fly   994 KELRLCRNELSDFPHIALYNLSTLESLDLARNQLASIDFFKLSGTLNLRQLI---------LRDN 1049
                     .:|.|.: |..:..|:.|||:.|   .|..:..:|:.|..:|.         |..|
  Fly   280 ---------ATDIPKL-LTGMWRLQRLDLSEN---IIGIYAAAGSDNTSELFILPNLMYMNLSAN 331

  Fly  1050 KITALSGFNAVNLTQLDSVDLSGNLLLSLPANF-LRHSINLQKVHLSNNRFLQIPSSALSDVSIP 1113
            ::|.|...:.:...:|..:|.|.|.:.: ||.. :..:.|||.:||.                  
  Fly   332 RLTRLHFDSPIPWERLTHLDASYNRIYA-PAKVGIDEAFNLQSLHLE------------------ 377

  Fly  1114 RLSWLNLTGNPINRIYTVKEERYPYLKELYICQTNLSILTSKDFEAFQALQHLHLVNNRITRISP 1178
                    ||.||.......:.:|.|||                        :.|.:|   :..|
  Fly   378 --------GNYINNFELTPWKPHPSLKE------------------------VALYDN---KFQP 407

  Fly  1179 GAFKSLTNLLTLDLSVNELEMLPKERLQGLRLLRFLNISHNT-------LKDLEEF--SVDLLEM 1234
            ..:|::|.... ::.||.||.....:            |:||       :.|..:|  |:.....
  Fly   408 KGYKNITKFFN-EIGVNVLEKTQYSQ------------SNNTTPTCKPCIPDARDFPTSISADTN 459

  Fly  1235 QTLDLSFNQLDRISKKTFR-NLHGLLELFLMGNRMTVLSNDAFRFLRKLHVLDLRKNYFELVPLE 1298
            ||:|...|.|   |..|:: |:..:|.|..:                   ::.|..|.|.:|.|.
  Fly   460 QTIDTKVNPL---SNDTYQWNVWNVLMLVSL-------------------IVSLFVNSFLIVKLI 502

  Fly  1299 PLR 1301
            .||
  Fly   503 RLR 505

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42346NP_001036303.2 leucine-rich repeat 303..325 CDD:275380
LRR_8 325..384 CDD:290566
leucine-rich repeat 327..350 CDD:275380
leucine-rich repeat 351..461 CDD:275380
LRR_8 373..433 CDD:290566
LRR_RI 397..648 CDD:238064 13/41 (32%)
leucine-rich repeat 399..422 CDD:275380
leucine-rich repeat 462..485 CDD:275380
LRR_8 465..520 CDD:290566
leucine-rich repeat 486..509 CDD:275380
LRR_8 508..567 CDD:290566
leucine-rich repeat 510..533 CDD:275380
LRR_RI 527..785 CDD:238064 42/178 (24%)
leucine-rich repeat 534..556 CDD:275380
LRR_8 555..613 CDD:290566 3/5 (60%)
leucine-rich repeat 557..580 CDD:275380
leucine-rich repeat 581..604 CDD:275380
LRR_8 604..663 CDD:290566 13/56 (23%)
leucine-rich repeat 605..628 CDD:275380 7/21 (33%)
leucine-rich repeat 629..652 CDD:275380 4/22 (18%)
LRR_8 652..711 CDD:290566 7/58 (12%)
leucine-rich repeat 653..676 CDD:275380 1/22 (5%)
leucine-rich repeat 677..700 CDD:275380 4/22 (18%)
leucine-rich repeat 701..748 CDD:275380 11/46 (24%)
leucine-rich repeat 725..736 CDD:275378 4/10 (40%)
leucine-rich repeat 749..772 CDD:275380 6/22 (27%)
LRR_8 771..831 CDD:290566 24/59 (41%)
leucine-rich repeat 773..793 CDD:275380 7/19 (37%)
LRR_RI 804..1076 CDD:238064 57/282 (20%)
LRR_8 821..903 CDD:290566 14/81 (17%)
leucine-rich repeat 821..844 CDD:275380 7/22 (32%)
leucine-rich repeat 845..868 CDD:275380 4/22 (18%)
leucine-rich repeat 869..892 CDD:275380 2/22 (9%)
leucine-rich repeat 893..915 CDD:275380 1/21 (5%)
leucine-rich repeat 916..944 CDD:275380 6/27 (22%)
leucine-rich repeat 945..968 CDD:275380 4/24 (17%)
LRR_8 967..1027 CDD:290566 14/59 (24%)
leucine-rich repeat 969..992 CDD:275380 6/22 (27%)
leucine-rich repeat 993..1014 CDD:275380 3/20 (15%)
LRR_8 1015..1075 CDD:290566 17/68 (25%)
leucine-rich repeat 1017..1040 CDD:275380 7/22 (32%)
leucine-rich repeat 1041..1064 CDD:275380 5/31 (16%)
LRR_RI <1047..1244 CDD:238064 41/206 (20%)
LRR_8 1063..1125 CDD:290566 13/62 (21%)
leucine-rich repeat 1089..1114 CDD:275380 4/24 (17%)
leucine-rich repeat 1115..1162 CDD:275380 8/46 (17%)
LRR_8 1163..1219 CDD:290566 10/55 (18%)
leucine-rich repeat 1163..1186 CDD:275380 4/22 (18%)
leucine-rich repeat 1187..1210 CDD:275380 4/22 (18%)
leucine-rich repeat 1211..1233 CDD:275380 6/30 (20%)
leucine-rich repeat 1234..1257 CDD:275380 8/23 (35%)
LRR_8 1235..1292 CDD:290566 12/57 (21%)
leucine-rich repeat 1258..1279 CDD:275380 2/20 (10%)
leucine-rich repeat 1282..1306 CDD:275380 7/20 (35%)
CG7800NP_649770.1 leucine-rich repeat 46..64 CDD:275380 5/46 (11%)
leucine-rich repeat 65..85 CDD:275380 4/32 (13%)
LRR_8 87..147 CDD:290566 19/70 (27%)
leucine-rich repeat 89..112 CDD:275380 8/22 (36%)
leucine-rich repeat 113..136 CDD:275380 6/22 (27%)
LRR_RI <131..334 CDD:238064 67/295 (23%)
leucine-rich repeat 137..160 CDD:275380 9/22 (41%)
LRR_8 140..195 CDD:290566 22/54 (41%)
leucine-rich repeat 161..184 CDD:275380 9/22 (41%)
leucine-rich repeat 185..208 CDD:275380 7/22 (32%)
leucine-rich repeat 209..246 CDD:275380 14/98 (14%)
leucine-rich repeat 247..267 CDD:275380 4/24 (17%)
leucine-rich repeat 268..292 CDD:275380 9/46 (20%)
leucine-rich repeat 293..322 CDD:275380 9/31 (29%)
leucine-rich repeat 395..406 CDD:275378 5/37 (14%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45453706
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR45617
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
22.030

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