DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG42346 and CG42709

DIOPT Version :9

Sequence 1:	NP_001036303.2	Gene:	CG42346 / 3355160	FlyBaseID:	FBgn0259677	Length:	1817	Species:	Drosophila melanogaster
Sequence 2:	NP_001163434.1	Gene:	CG42709 / 39453	FlyBaseID:	FBgn0261674	Length:	458	Species:	Drosophila melanogaster

Alignment Length:	293	Identity:	75/293 - (25%)
Similarity:	114/293 - (38%)	Gaps:	50/293 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   355 DFDYNEIVRVDDYSFYGLRISKLNMKGNRLQGMPEHAFAGLEECMQEIDVSENGLRTF-PLMAL- 417
            ||:|.:    ||||.............|||  ||:.:             |.:...|| |:..:
  Fly    37 DFNYGD----DDYSETATGEESPETAENRL--MPQSS-------------STSTTTTFRPIFNIP 82

  Fly   418 RKLDHLRILRLSNNRIPTFYGDIQLATNNASAAAAAVGAFQLPSLIFLDLSSNQFAEIGPDCFRA 482
            |:.:|  :|..|..|......|.:. ...|:|....|......:...:|||.|..||:.|:.|..
  Fly    83 RRSNH--VLEPSCPRNCLCLEDFKF-VQCANAHLTHVPLDMPKTAAIIDLSHNVIAELRPEDFAN 144

  Fly   483 FPQLKTLSFYANQIELVQPEAFKSLRELMSLDMSHNRIIGLDPKVFEKNKRLQTVDLSHNHI-HT 546
            ..:...::...|.|..:..:.|:....|..|.:::||:..:||..|...|.|..:|||:|.| ..
  Fly   145 LSRAVEINLNHNLISSIDKDVFQGSERLKRLRLANNRLTKIDPDTFAAAKELTLLDLSNNTITQR 209

  Fly   547 IGGVFSNLPQLREVFLSENNILELPADAFTNSTNVDVIYLESNAI-AHIDPNVFSTLVNLDHLYL 610
            :.|.|.|.|.|.|......:..|||...|.|.:.::|:.|..|.. ..|:...||.|
  Fly   210 LDGSFLNQPDLVEFSCVNCSWTELPEQTFQNMSGLEVLRLNKNDFKQQINTKAFSPL-------- 266

  Fly   611 RSNFIPLLPVTLFDKSTKLTSLSLDNNEIQDLE 643
                            ||:..|.|...|.|::|
  Fly   267 ----------------TKIIKLKLPELEQQNIE 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42346	NP_001036303.2	leucine-rich repeat	303..325	CDD:275380
		LRR_8	325..384	CDD:290566	8/28 (29%)
		leucine-rich repeat	327..350	CDD:275380
		leucine-rich repeat	351..461	CDD:275380	25/107 (23%)
		LRR_8	373..433	CDD:290566	13/61 (21%)
		LRR_RI	397..648	CDD:238064	63/251 (25%)
		leucine-rich repeat	399..422	CDD:275380	5/24 (21%)
		leucine-rich repeat	462..485	CDD:275380	8/22 (36%)
		LRR_8	465..520	CDD:290566	14/54 (26%)
		leucine-rich repeat	486..509	CDD:275380	3/22 (14%)
		LRR_8	508..567	CDD:290566	20/59 (34%)
		leucine-rich repeat	510..533	CDD:275380	7/22 (32%)
		LRR_RI	527..785	CDD:238064	33/119 (28%)
		leucine-rich repeat	534..556	CDD:275380	9/22 (41%)
		LRR_8	555..613	CDD:290566	15/58 (26%)
		leucine-rich repeat	557..580	CDD:275380	7/22 (32%)
		leucine-rich repeat	581..604	CDD:275380	7/23 (30%)
		LRR_8	604..663	CDD:290566	7/40 (18%)
		leucine-rich repeat	605..628	CDD:275380	0/22 (0%)
		leucine-rich repeat	629..652	CDD:275380	5/15 (33%)
		LRR_8	652..711	CDD:290566
		leucine-rich repeat	653..676	CDD:275380
		leucine-rich repeat	677..700	CDD:275380
		leucine-rich repeat	701..748	CDD:275380
		leucine-rich repeat	725..736	CDD:275378
		leucine-rich repeat	749..772	CDD:275380
		LRR_8	771..831	CDD:290566
		leucine-rich repeat	773..793	CDD:275380
		LRR_RI	804..1076	CDD:238064
		LRR_8	821..903	CDD:290566
		leucine-rich repeat	821..844	CDD:275380
		leucine-rich repeat	845..868	CDD:275380
		leucine-rich repeat	869..892	CDD:275380
		leucine-rich repeat	893..915	CDD:275380
		leucine-rich repeat	916..944	CDD:275380
		leucine-rich repeat	945..968	CDD:275380
		LRR_8	967..1027	CDD:290566
		leucine-rich repeat	969..992	CDD:275380
		leucine-rich repeat	993..1014	CDD:275380
		LRR_8	1015..1075	CDD:290566
		leucine-rich repeat	1017..1040	CDD:275380
		leucine-rich repeat	1041..1064	CDD:275380
		LRR_RI	<1047..1244	CDD:238064
		LRR_8	1063..1125	CDD:290566
		leucine-rich repeat	1089..1114	CDD:275380
		leucine-rich repeat	1115..1162	CDD:275380
		LRR_8	1163..1219	CDD:290566
		leucine-rich repeat	1163..1186	CDD:275380
		leucine-rich repeat	1187..1210	CDD:275380
		leucine-rich repeat	1211..1233	CDD:275380
		leucine-rich repeat	1234..1257	CDD:275380
		LRR_8	1235..1292	CDD:290566
		leucine-rich repeat	1258..1279	CDD:275380
		leucine-rich repeat	1282..1306	CDD:275380
CG42709	NP_001163434.1	LRR_8	126..182	CDD:290566	14/55 (25%)
		leucine-rich repeat	128..147	CDD:275380	8/18 (44%)
		leucine-rich repeat	148..171	CDD:275380	3/22 (14%)
		LRR_RI	<150..225	CDD:238064	23/74 (31%)
		LRR_8	171..254	CDD:290566	28/82 (34%)
		leucine-rich repeat	172..195	CDD:275380	7/22 (32%)
		leucine-rich repeat	196..219	CDD:275380	9/22 (41%)
		leucine-rich repeat	220..243	CDD:275380	7/22 (32%)
		leucine-rich repeat	244..268	CDD:275380	7/47 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453695
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930