DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG42346 and CG7509

DIOPT Version :9

Sequence 1:NP_001036303.2 Gene:CG42346 / 3355160 FlyBaseID:FBgn0259677 Length:1817 Species:Drosophila melanogaster
Sequence 2:NP_647931.1 Gene:CG7509 / 38579 FlyBaseID:FBgn0035575 Length:615 Species:Drosophila melanogaster


Alignment Length:715 Identity:177/715 - (24%)
Similarity:275/715 - (38%) Gaps:194/715 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   821 LEELSLARNHIEAIEGYAFAKLKNLKSLDLSHNPLVQLTRDIFSNEF------PLNSLNLGNCSL 879
            |..|.|..:..|.|.|.:.||...::|||                ||      ||.|.:..||||
  Fly     8 LVSLVLLMDPAEVITGPSQAKEPPIQSLD----------------EFRQRYLLPLISSDTRNCSL 56

  Fly   880 RKLEQHAFKSLTNLNELNLERNQL-NPADIQTLDIPNLRRLLLSHNNFSY-AGSVGIMAGMLD-- 940
                 :|.:||..:::|.:..|.: |.......|....:.....||:... .|.:..|:.:.:  
  Fly    57 -----NACESLGIVSQLLMLINSMPNGTQSAANDKKPPKSKANGHNDGDVNGGEINAMSHLANFD 116

  Fly   941 ----------RLRSLQ----------QLSMSNCSLGQI---PDL--LFAKNTNL----------- 969
                      ||||::          |:..::|:.|..   ||.  ....||||           
  Fly   117 LVKRVRQIESRLRSVEQPVWHLATGSQIEWNHCTSGVCRCNPDTKSFTCWNTNLKSVPVTQVIPM 181

  Fly   970 --VRLDLCDNRLTQINRNIFSGLNVFKELRLCRNELSDFPHIALYNLSTLESLDLARNQLASID- 1031
              |.:||..|.|:.::::.|.||.|.|||.:..|.|...|.....:|.:|..|.:..|||..|| 
  Fly   182 NMVNIDLSRNILSTLHKDTFRGLTVLKELDISHNVLDFLPFDLFQDLDSLLVLRIQNNQLEDIDH 246

  Fly  1032 --FFKLSGTLNLRQLILRDNKITALSG---FNAVNLTQLDSVDLSGNLLLSLPANFLRHSINLQK 1091
              |:||.   ||..|.|..|:|..|..   ::|..||.::..|   |.:.:.|.|.||..:.|::
  Fly   247 RTFWKLR---NLNILDLSKNEIGMLPESIFYHAQRLTVINMCD---NQIQNFPPNLLRDQLMLEE 305

  Fly  1092 VHLSNNRFLQIPSSALSDVSIPRLSWLNLTGNPINRIYTVKEERYPYLKELYICQTNLSILTSKD 1156
            :.:|.|:..::.|.::.  .:.:|..|:...|.|.:|                         ..|
  Fly   306 LDMSRNKISELSSGSIR--YLTKLKTLDFGWNQIAKI-------------------------DDD 343

  Fly  1157 FEA-FQALQHLHLVNNRITRISPGAFKSLTNLLTLDLSVNELEMLPKERLQGLRLLRFLNISHNT 1220
            |.| .::|:.|.|.||||:.:|...|.:|.||:||||:.|                |..:|..|.
  Fly   344 FFAGLRSLRTLSLHNNRISSLSGTIFNNLANLVTLDLTTN----------------RISHIDGNA 392

  Fly  1221 LKDLEEFSVDLLEMQTLDLSFNQLDRISKKTFRNLHGLLELFLMGNRMTVLSNDAFRFLRKLHVL 1285
            .       |:|..:..|.|..|.:..|....|.|:..|..|.|..|.:|.|..|.|:.|..|.:|
  Fly   393 F-------VELNNLNELFLGQNSMSSIPADLFLNVSALTRLTLFSNNLTTLEADDFQGLNNLKIL 450

  Fly  1286 DLRKNY---FELVPLEPLRPLE--------------------TNLRTLRLEENPLHCSCDAQKLW 1327
            .|..|.   |:....|||..||                    .||..::|::||.||.|.|..|.
  Fly   451 LLNNNILKNFDARAFEPLSQLEKLRIDSNKLMFLPHGALHGLKNLVAVKLDKNPWHCDCRALYLA 515

  Fly  1328 EWLRDHRKWSLSMGSGAGRGIGGLTGGLGGDSINYLRCEHPTELRGKVFGRMEPQQFCD------ 1386
            .|:|:   :.|.:..|                 ....|..|.:|.|...|.:.....||      
  Fly   516 RWIRE---FVLKLWDG-----------------QQPMCRGPGDLGGHEVGLLRYDDLCDGQWASM 560

  Fly  1387 ---APLIPKMAIQDIQPYSVVVSWQSRDHLGLNGFEIVYHATGDGLVTAGSPTSRERDSLRDIHD 1448
               :|.:|      ::.:.:.......|:..|. .:.:|:.|.|..:.....||   .|::.:|:
  Fly   561 LSLSPRLP------VRKHQISTPMNYTDYFNLY-LKHIYNGTTDEELKEADITS---VSIKKVHN 615

  Fly  1449  1448
              Fly   616  615

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42346NP_001036303.2 leucine-rich repeat 303..325 CDD:275380
LRR_8 325..384 CDD:290566
leucine-rich repeat 327..350 CDD:275380
leucine-rich repeat 351..461 CDD:275380
LRR_8 373..433 CDD:290566
LRR_RI 397..648 CDD:238064
leucine-rich repeat 399..422 CDD:275380
leucine-rich repeat 462..485 CDD:275380
LRR_8 465..520 CDD:290566
leucine-rich repeat 486..509 CDD:275380
LRR_8 508..567 CDD:290566
leucine-rich repeat 510..533 CDD:275380
LRR_RI 527..785 CDD:238064
leucine-rich repeat 534..556 CDD:275380
LRR_8 555..613 CDD:290566
leucine-rich repeat 557..580 CDD:275380
leucine-rich repeat 581..604 CDD:275380
LRR_8 604..663 CDD:290566
leucine-rich repeat 605..628 CDD:275380
leucine-rich repeat 629..652 CDD:275380
LRR_8 652..711 CDD:290566
leucine-rich repeat 653..676 CDD:275380
leucine-rich repeat 677..700 CDD:275380
leucine-rich repeat 701..748 CDD:275380
leucine-rich repeat 725..736 CDD:275378
leucine-rich repeat 749..772 CDD:275380
LRR_8 771..831 CDD:290566 3/9 (33%)
leucine-rich repeat 773..793 CDD:275380
LRR_RI 804..1076 CDD:238064 82/308 (27%)
LRR_8 821..903 CDD:290566 25/87 (29%)
leucine-rich repeat 821..844 CDD:275380 8/22 (36%)
leucine-rich repeat 845..868 CDD:275380 5/28 (18%)
leucine-rich repeat 869..892 CDD:275380 9/22 (41%)
leucine-rich repeat 893..915 CDD:275380 4/22 (18%)
leucine-rich repeat 916..944 CDD:275380 6/40 (15%)
leucine-rich repeat 945..968 CDD:275380 6/37 (16%)
LRR_8 967..1027 CDD:290566 22/72 (31%)
leucine-rich repeat 969..992 CDD:275380 9/35 (26%)
leucine-rich repeat 993..1014 CDD:275380 6/20 (30%)
LRR_8 1015..1075 CDD:290566 22/65 (34%)
leucine-rich repeat 1017..1040 CDD:275380 10/25 (40%)
leucine-rich repeat 1041..1064 CDD:275380 8/25 (32%)
LRR_RI <1047..1244 CDD:238064 49/200 (25%)
LRR_8 1063..1125 CDD:290566 14/61 (23%)
leucine-rich repeat 1089..1114 CDD:275380 4/24 (17%)
leucine-rich repeat 1115..1162 CDD:275380 8/47 (17%)
LRR_8 1163..1219 CDD:290566 19/55 (35%)
leucine-rich repeat 1163..1186 CDD:275380 10/22 (45%)
leucine-rich repeat 1187..1210 CDD:275380 6/22 (27%)
leucine-rich repeat 1211..1233 CDD:275380 5/21 (24%)
leucine-rich repeat 1234..1257 CDD:275380 6/22 (27%)
LRR_8 1235..1292 CDD:290566 19/59 (32%)
leucine-rich repeat 1258..1279 CDD:275380 8/20 (40%)
leucine-rich repeat 1282..1306 CDD:275380 10/46 (22%)
CG7509NP_647931.1 LRR_8 182..241 CDD:290566 19/58 (33%)
leucine-rich repeat 187..206 CDD:275380 7/18 (39%)
LRR_RI <201..386 CDD:238064 67/233 (29%)
leucine-rich repeat 207..230 CDD:275380 7/22 (32%)
leucine-rich repeat 231..254 CDD:275380 10/25 (40%)
LRR_8 253..313 CDD:290566 19/65 (29%)
leucine-rich repeat 255..278 CDD:275380 7/22 (32%)
leucine-rich repeat 279..302 CDD:275380 8/25 (32%)
LRR_8 303..361 CDD:290566 17/84 (20%)
leucine-rich repeat 303..326 CDD:275380 4/24 (17%)
leucine-rich repeat 327..350 CDD:275380 8/47 (17%)
LRR_8 349..407 CDD:290566 24/80 (30%)
LRR_4 350..390 CDD:289563 19/55 (35%)
leucine-rich repeat 351..374 CDD:275380 10/22 (45%)
leucine-rich repeat 375..398 CDD:275380 11/45 (24%)
LRR_8 398..>443 CDD:290566 14/44 (32%)
leucine-rich repeat 399..422 CDD:275380 6/22 (27%)
leucine-rich repeat 423..443 CDD:275380 8/19 (42%)
leucine-rich repeat 471..494 CDD:275380 2/22 (9%)
LRRCT 503..554 CDD:214507 16/70 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - otm42484
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.910

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