DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG42346 and CG4781

DIOPT Version :9

Sequence 1:NP_001036303.2 Gene:CG42346 / 3355160 FlyBaseID:FBgn0259677 Length:1817 Species:Drosophila melanogaster
Sequence 2:NP_611951.1 Gene:CG4781 / 37943 FlyBaseID:FBgn0035043 Length:469 Species:Drosophila melanogaster


Alignment Length:471 Identity:115/471 - (24%)
Similarity:168/471 - (35%) Gaps:155/471 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly  1084 RHSINLQKVHLS--NNRFLQIPSS----ALSDVS--IP------RLSWLNLTGNPINRIYTVKEE 1134
            |.|.....|..|  .||.|:|..|    .::|:|  :|      .|||..|...|   |:|... 
  Fly    48 RRSCECSNVSASPWGNRALRIDCSYKDYKVADLSLLLPLYIDSLDLSWNALDSVP---IFTSDS- 108

  Fly  1135 RYPYLKELYICQTNLSILTSKDFEAFQALQHLHLVNNRITRISPGAFKSLTNLLTLDLSVNELEM 1199
                |.:|.:...|:|.|.|.:|:...:|:.|:|..|.|.::..|:|..|.:|..|||:.|.|.:
  Fly   109 ----LHQLNLRHNNISQLVSGNFKQLTSLRELYLGWNSIGKLESGSFDGLPHLQVLDLAHNNLHL 169

  Fly  1200 LPKERLQGLRLLRFLNISHN----------------------------TLKD--------LEEFS 1228
            ||......|.:|..|:||.|                            :|.|        |:|.|
  Fly   170 LPGHLFAPLLVLGTLDISWNRRFNESGGDLYTGLGVNWKLSTLRLDACSLNDLHLPVNAPLKELS 234

  Fly  1229 V---DLLEMQT--------LDLSFNQLDRISKKTFRNLHGLLELFL---------MGNRMT---V 1270
            :   .|..:.|        ||:|.|.|:.:..:...||..:.:||:         :.|.:|   |
  Fly   235 LRRNQLKRIPTQLPETLLRLDISDNLLEELLPEDTANLTQVRQLFIEDMPVLQRVVANSLTHVDV 299

  Fly  1271 LSNDAFRFLRKLHVLD----------------LRKNYFELVPL----EPLRPLETNLRTLRLEEN 1315
            |...:|:..|:|..||                ||...|....|    ..|.|:.|.|..|.|...
  Fly   300 LETLSFQNSRQLSHLDAEAFGPIMTTPTKKRALRSLSFRGTMLRTFNSTLAPIFTQLAELDLNGL 364

  Fly  1316 PLHCSCDAQKLWEWLRDHRKWSLSMGSGAGRGIGGLTGGLGGDSINYLRCEHPTELRGKVFGRME 1380
            ||.|.|:.    .||:.               :...|.|         ||..|..:||.:.....
  Fly   365 PLQCDCEL----VWLKQ---------------LPVQTNG---------RCYKPARIRGMLVTSAR 401

  Fly  1381 PQQF-CDA--------PLIPKMAIQDIQPYSVVVSWQSRDHLGLNGFEIVYHATGDGLVTAGSPT 1436
            ...| ||.        .::..:|:.....|.:|:.  .|.|.|:         |....|.||||.
  Fly   402 GDAFSCDTWPRWAYGLVVLSLIALSAAGIYLIVMG--LRPHRGV---------TMRRKVGAGSPY 455

  Fly  1437 SRERDSLRDIHDPERQ 1452
            :|.      ..:|.||
  Fly   456 ARV------TIEPNRQ 465

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42346NP_001036303.2 leucine-rich repeat 303..325 CDD:275380
LRR_8 325..384 CDD:290566
leucine-rich repeat 327..350 CDD:275380
leucine-rich repeat 351..461 CDD:275380
LRR_8 373..433 CDD:290566
LRR_RI 397..648 CDD:238064
leucine-rich repeat 399..422 CDD:275380
leucine-rich repeat 462..485 CDD:275380
LRR_8 465..520 CDD:290566
leucine-rich repeat 486..509 CDD:275380
LRR_8 508..567 CDD:290566
leucine-rich repeat 510..533 CDD:275380
LRR_RI 527..785 CDD:238064
leucine-rich repeat 534..556 CDD:275380
LRR_8 555..613 CDD:290566
leucine-rich repeat 557..580 CDD:275380
leucine-rich repeat 581..604 CDD:275380
LRR_8 604..663 CDD:290566
leucine-rich repeat 605..628 CDD:275380
leucine-rich repeat 629..652 CDD:275380
LRR_8 652..711 CDD:290566
leucine-rich repeat 653..676 CDD:275380
leucine-rich repeat 677..700 CDD:275380
leucine-rich repeat 701..748 CDD:275380
leucine-rich repeat 725..736 CDD:275378
leucine-rich repeat 749..772 CDD:275380
LRR_8 771..831 CDD:290566
leucine-rich repeat 773..793 CDD:275380
LRR_RI 804..1076 CDD:238064
LRR_8 821..903 CDD:290566
leucine-rich repeat 821..844 CDD:275380
leucine-rich repeat 845..868 CDD:275380
leucine-rich repeat 869..892 CDD:275380
leucine-rich repeat 893..915 CDD:275380
leucine-rich repeat 916..944 CDD:275380
leucine-rich repeat 945..968 CDD:275380
LRR_8 967..1027 CDD:290566
leucine-rich repeat 969..992 CDD:275380
leucine-rich repeat 993..1014 CDD:275380
LRR_8 1015..1075 CDD:290566
leucine-rich repeat 1017..1040 CDD:275380
leucine-rich repeat 1041..1064 CDD:275380
LRR_RI <1047..1244 CDD:238064 59/220 (27%)
LRR_8 1063..1125 CDD:290566 16/54 (30%)
leucine-rich repeat 1089..1114 CDD:275380 10/38 (26%)
leucine-rich repeat 1115..1162 CDD:275380 14/46 (30%)
LRR_8 1163..1219 CDD:290566 21/55 (38%)
leucine-rich repeat 1163..1186 CDD:275380 8/22 (36%)
leucine-rich repeat 1187..1210 CDD:275380 9/22 (41%)
leucine-rich repeat 1211..1233 CDD:275380 11/60 (18%)
leucine-rich repeat 1234..1257 CDD:275380 8/30 (27%)
LRR_8 1235..1292 CDD:290566 21/92 (23%)
leucine-rich repeat 1258..1279 CDD:275380 7/32 (22%)
leucine-rich repeat 1282..1306 CDD:275380 9/43 (21%)
CG4781NP_611951.1 leucine-rich repeat 90..108 CDD:275380 7/20 (35%)
LRR_8 108..167 CDD:290566 20/63 (32%)
leucine-rich repeat 109..132 CDD:275380 7/22 (32%)
LRR_RI <121..>261 CDD:238064 36/139 (26%)
leucine-rich repeat 133..156 CDD:275380 8/22 (36%)
leucine-rich repeat 157..180 CDD:275380 9/22 (41%)
leucine-rich repeat 181..208 CDD:275380 5/26 (19%)
leucine-rich repeat 230..253 CDD:275380 5/22 (23%)
leucine-rich repeat 254..274 CDD:275380 7/19 (37%)
leucine-rich repeat 275..299 CDD:275380 4/23 (17%)
leucine-rich repeat 300..319 CDD:275380 6/18 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR45617
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
11.100

Return to query results.
Submit another query.