Protein Alignment CG42346 and CG4781

DIOPT Version :10

• Sequence 1: NP_001036303.2
• Gene: CG42346 / 3355160
• FlyBaseID: FBgn0259677
• Length: 1817
• Species: Drosophila melanogaster
• Sequence 2: NP_611951.1
• Gene: CG4781 / 37943
• FlyBaseID: FBgn0035043
• Length: 469
• Species: Drosophila melanogaster
• Alignment Length: 471
• Identity: 115/471 - (24%)
• Similarity: 168/471 - (35%)
• Gaps: 155/471 - (32%)

  Fly  1084 RHSINLQKVHLS--NNRFLQIPSS----ALSDVS--IP------RLSWLNLTGNPINRIYTVKEE 1134
            |.|.....|..|  .||.|:|..|    .::|:|  :|      .|||..|...|   |:|...
  Fly    48 RRSCECSNVSASPWGNRALRIDCSYKDYKVADLSLLLPLYIDSLDLSWNALDSVP---IFTSDS- 108

  Fly  1135 RYPYLKELYICQTNLSILTSKDFEAFQALQHLHLVNNRITRISPGAFKSLTNLLTLDLSVNELEM 1199
                |.:|.:...|:|.|.|.:|:...:|:.|:|..|.|.::..|:|..|.:|..|||:.|.|.:
  Fly   109 ----LHQLNLRHNNISQLVSGNFKQLTSLRELYLGWNSIGKLESGSFDGLPHLQVLDLAHNNLHL 169

  Fly  1200 LPKERLQGLRLLRFLNISHN----------------------------TLKD--------LEEFS 1228
            ||......|.:|..|:||.|                            :|.|        |:|.|
  Fly   170 LPGHLFAPLLVLGTLDISWNRRFNESGGDLYTGLGVNWKLSTLRLDACSLNDLHLPVNAPLKELS 234

  Fly  1229 V---DLLEMQT--------LDLSFNQLDRISKKTFRNLHGLLELFL---------MGNRMT---V 1270
            :   .|..:.|        ||:|.|.|:.:..:...||..:.:||:         :.|.:|   |
  Fly   235 LRRNQLKRIPTQLPETLLRLDISDNLLEELLPEDTANLTQVRQLFIEDMPVLQRVVANSLTHVDV 299

  Fly  1271 LSNDAFRFLRKLHVLD----------------LRKNYFELVPL----EPLRPLETNLRTLRLEEN 1315
            |...:|:..|:|..||                ||...|....|    ..|.|:.|.|..|.|...
  Fly   300 LETLSFQNSRQLSHLDAEAFGPIMTTPTKKRALRSLSFRGTMLRTFNSTLAPIFTQLAELDLNGL 364

  Fly  1316 PLHCSCDAQKLWEWLRDHRKWSLSMGSGAGRGIGGLTGGLGGDSINYLRCEHPTELRGKVFGRME 1380
            ||.|.|:.    .||:.               :...|.|         ||..|..:||.:.....
  Fly   365 PLQCDCEL----VWLKQ---------------LPVQTNG---------RCYKPARIRGMLVTSAR 401

  Fly  1381 PQQF-CDA--------PLIPKMAIQDIQPYSVVVSWQSRDHLGLNGFEIVYHATGDGLVTAGSPT 1436
            ...| ||.        .::..:|:.....|.:|:.  .|.|.|:         |....|.||||.
  Fly   402 GDAFSCDTWPRWAYGLVVLSLIALSAAGIYLIVMG--LRPHRGV---------TMRRKVGAGSPY 455

  Fly  1437 SRERDSLRDIHDPERQ 1452
            :|.      ..:|.||
  Fly   456 ARV------TIEPNRQ 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42346	NP_001036303.2	LRR	<301..606	CDD:443914
		leucine-rich repeat	303..325	CDD:275380
		leucine-rich repeat	327..350	CDD:275380
		leucine-rich repeat	351..461	CDD:275380
		leucine-rich repeat	399..422	CDD:275380
		leucine-rich repeat	462..485	CDD:275380
		LRR	486..>736	CDD:443914
		leucine-rich repeat	486..509	CDD:275380
		leucine-rich repeat	510..533	CDD:275380
		leucine-rich repeat	534..556	CDD:275380
		leucine-rich repeat	557..580	CDD:275380
		leucine-rich repeat	581..604	CDD:275380
		leucine-rich repeat	605..628	CDD:275380
		PPP1R42	627..860	CDD:455733
		leucine-rich repeat	629..652	CDD:275380
		leucine-rich repeat	653..676	CDD:275380
		leucine-rich repeat	677..700	CDD:275380
		leucine-rich repeat	701..748	CDD:275380
		leucine-rich repeat	725..736	CDD:275378
		leucine-rich repeat	749..772	CDD:275380
		leucine-rich repeat	773..793	CDD:275380
		leucine-rich repeat	821..844	CDD:275380
		leucine-rich repeat	845..868	CDD:275380
		LRR	869..1226	CDD:443914	51/191 (27%)
		leucine-rich repeat	869..892	CDD:275380
		leucine-rich repeat	893..915	CDD:275380
		leucine-rich repeat	916..944	CDD:275380
		leucine-rich repeat	945..968	CDD:275380
		leucine-rich repeat	969..992	CDD:275380
		leucine-rich repeat	993..1014	CDD:275380
		leucine-rich repeat	1017..1040	CDD:275380
		leucine-rich repeat	1041..1064	CDD:275380
		leucine-rich repeat	1089..1114	CDD:275380	10/38 (26%)
		leucine-rich repeat	1115..1162	CDD:275380	14/46 (30%)
		PPP1R42	1155..1317	CDD:455733	58/240 (24%)
		leucine-rich repeat	1163..1186	CDD:275380	8/22 (36%)
		leucine-rich repeat	1187..1210	CDD:275380	9/22 (41%)
		leucine-rich repeat	1211..1233	CDD:275380	11/60 (18%)
		leucine-rich repeat	1234..1257	CDD:275380	8/30 (27%)
		leucine-rich repeat	1258..1279	CDD:275380	7/32 (22%)
		leucine-rich repeat	1282..1306	CDD:275380	9/43 (21%)
CG4781	NP_611951.1	LRR	<90..367	CDD:443914	72/284 (25%)
		leucine-rich repeat	90..108	CDD:275380	7/20 (35%)
		leucine-rich repeat	109..132	CDD:275380	7/22 (32%)
		leucine-rich repeat	133..156	CDD:275380	8/22 (36%)
		leucine-rich repeat	157..180	CDD:275380	9/22 (41%)
		leucine-rich repeat	181..208	CDD:275380	5/26 (19%)
		leucine-rich repeat	230..253	CDD:275380	5/22 (23%)
		leucine-rich repeat	254..274	CDD:275380	7/19 (37%)
		leucine-rich repeat	275..299	CDD:275380	4/23 (17%)
		leucine-rich repeat	300..319	CDD:275380	6/18 (33%)