Protein Alignment CG42346 and Rxfp1

DIOPT Version :10

• Sequence 1: NP_001036303.2
• Gene: CG42346 / 3355160
• FlyBaseID: FBgn0259677
• Length: 1817
• Species: Drosophila melanogaster
• Sequence 2: XP_006232570.1
• Gene: Rxfp1 / 295144
• RGDID: 1302973
• Length: 763
• Species: Rattus norvegicus
• Alignment Length: 411
• Identity: 103/411 - (25%)
• Similarity: 168/411 - (40%)
• Gaps: 77/411 - (18%)

  Fly   548 GGVFSNLPQL-------------REVFLSENNILELPADA-FTNSTNVDVIYLESNAIAHIDPNV 598
            |.:...||||             .|....:||...|..|. |.|       |.:..:...|:...
  Rat    41 GNISKCLPQLLHCNGVDDCGNQADEDNCGDNNGWSLQLDKYFAN-------YYKLTSTNSIEAET 98

  Fly   599 FSTLV--------------NLDHLYLRSNFIPLLPVTLFDKSTKLTSLSLDNNEIQDLEIGMFRK 649
            ...||              :.|...||:  :|.:       |:.:|.:||..|.|:.|....||.
  Rat    99 SECLVGSVPMHCLCRDLELDCDEANLRA--VPSV-------SSNVTVMSLQWNFIRTLPPNSFRM 154

  Fly   650 LEHLREVRLHNNRIRRVRRGVFEPLPSLQELHIQKNSIEDIEPQAFHTLENMQHINLQDNQLTVL 714
            ...|:::.|.||:||.|....|..|.||.:|::..|.|..::|..|..|..::.:.::|
  Rat   155 YHDLQKLCLQNNKIRSVSVSAFRGLHSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIED------ 213

  Fly   715 EDIFPDENSSLLSVQLEANYLHKVHPRTFSRQQKVQIMWLKDNQLTRV-ERSFFADTPQLGRLYL 778
                              |:|.::.|.||.....:.::.|.:|.|||: ::......|:|..|..
  Rat   214 ------------------NHLSRISPLTFYGLNSLILLVLMNNALTRLPDKPLCQHMPRLHWLDF 260

  Fly   779 SDNKIRDIEKDTFVNLLLLQFLDLSGNQLRQLRRDYFAPLQDLEELSLARNHIEAIEGYAFAKLK 843
            ..|:|.::...||::...|..|.:..|::..|....|..||.|:||.|..|.||.:....|..||
  Rat   261 EGNRIHNLRNLTFISCNNLTVLVMRKNKINHLNEHAFTHLQKLDELDLGSNKIENLPPNIFKDLK 325

  Fly   844 NLKSLDLSHNPLVQLTRDIFSNEFPLNSLNLGNCSLRKLEQHAFKSLTNLNELNLERNQ------ 902
            .|..|::|:||:.::..:.|.....|.|| |....:..::|..|:.|.||:.:..::.|
  Rat   326 ELSQLNISYNPIQKIEVNQFDYLAKLKSL-LEGIEISNIQQRMFRPLINLSHIYFKKFQYCGYAP 389

  Fly   903 -LNPADIQTLDIPNLRRLLLS 922
             :......|..|.:|..||.|
  Rat   390 HVRSCKPNTDGISSLENLLAS 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42346	NP_001036303.2	LRR	<301..606	CDD:443914	16/85 (19%)
		leucine-rich repeat	303..325	CDD:275380
		leucine-rich repeat	327..350	CDD:275380
		leucine-rich repeat	351..461	CDD:275380
		leucine-rich repeat	399..422	CDD:275380
		leucine-rich repeat	462..485	CDD:275380
		LRR	486..>736	CDD:443914	48/215 (22%)
		leucine-rich repeat	486..509	CDD:275380
		leucine-rich repeat	510..533	CDD:275380
		leucine-rich repeat	534..556	CDD:275380	2/7 (29%)
		leucine-rich repeat	557..580	CDD:275380	8/36 (22%)
		leucine-rich repeat	581..604	CDD:275380	4/36 (11%)
		leucine-rich repeat	605..628	CDD:275380	5/22 (23%)
		PPP1R42	627..860	CDD:455733	65/233 (28%)
		leucine-rich repeat	629..652	CDD:275380	8/22 (36%)
		leucine-rich repeat	653..676	CDD:275380	9/22 (41%)
		leucine-rich repeat	677..700	CDD:275380	7/22 (32%)
		leucine-rich repeat	701..748	CDD:275380	6/46 (13%)
		leucine-rich repeat	725..736	CDD:275378	1/10 (10%)
		leucine-rich repeat	749..772	CDD:275380	5/23 (22%)
		leucine-rich repeat	773..793	CDD:275380	6/19 (32%)
		leucine-rich repeat	821..844	CDD:275380	9/22 (41%)
		leucine-rich repeat	845..868	CDD:275380	6/22 (27%)
		LRR	869..1226	CDD:443914	16/61 (26%)
		leucine-rich repeat	869..892	CDD:275380	7/22 (32%)
		leucine-rich repeat	893..915	CDD:275380	4/28 (14%)
		leucine-rich repeat	916..944	CDD:275380	4/7 (57%)
		leucine-rich repeat	945..968	CDD:275380
		leucine-rich repeat	969..992	CDD:275380
		leucine-rich repeat	993..1014	CDD:275380
		leucine-rich repeat	1017..1040	CDD:275380
		leucine-rich repeat	1041..1064	CDD:275380
		leucine-rich repeat	1089..1114	CDD:275380
		leucine-rich repeat	1115..1162	CDD:275380
		PPP1R42	1155..1317	CDD:455733
		leucine-rich repeat	1163..1186	CDD:275380
		leucine-rich repeat	1187..1210	CDD:275380
		leucine-rich repeat	1211..1233	CDD:275380
		leucine-rich repeat	1234..1257	CDD:275380
		leucine-rich repeat	1258..1279	CDD:275380
		leucine-rich repeat	1282..1306	CDD:275380
Rxfp1	XP_006232570.1	LDLa	33..68	CDD:238060	6/26 (23%)
		leucine-rich repeat	134..157	CDD:275380	8/22 (36%)
		LRR	<157..>381	CDD:443914	67/248 (27%)
		leucine-rich repeat	158..181	CDD:275380	9/22 (41%)
		leucine-rich repeat	182..205	CDD:275380	7/22 (32%)
		leucine-rich repeat	206..229	CDD:275380	6/46 (13%)
		leucine-rich repeat	230..254	CDD:275380	5/23 (22%)
		leucine-rich repeat	255..278	CDD:275380	6/22 (27%)
		leucine-rich repeat	279..302	CDD:275380	6/22 (27%)
		leucine-rich repeat	303..326	CDD:275380	9/22 (41%)
		leucine-rich repeat	327..350	CDD:275380	6/22 (27%)
		leucine-rich repeat	351..371	CDD:275380	6/20 (30%)
		7tm_GPCRs	411..697	CDD:475119	103/411 (25%)
		TM helix 1	413..437	CDD:320631
		TM helix 2	446..467	CDD:320631
		TM helix 3	491..513	CDD:320631
		TM helix 4	535..551	CDD:320631
		TM helix 5	583..606	CDD:320631
		TM helix 6	632..654	CDD:320631
		TM helix 7	665..690	CDD:320631