DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG42346 and Lrrc15

DIOPT Version :9

Sequence 1:NP_001036303.2 Gene:CG42346 / 3355160 FlyBaseID:FBgn0259677 Length:1817 Species:Drosophila melanogaster
Sequence 2:NP_659551.1 Gene:Lrrc15 / 246296 RGDID:70551 Length:578 Species:Rattus norvegicus


Alignment Length:442 Identity:134/442 - (30%)
Similarity:197/442 - (44%) Gaps:46/442 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly   511 MSLDMSHNRIIGLDPKVFEKNKRLQTVDLSHNHIHTI-GGVFSNLPQLREVFLSENNILELPADA 574
            |||.:.:..|..|...:|.....|..:.:..|.:.|| .|.|.||..||.:.|:.|.:..||...
  Rat    56 MSLQVVNTHITELPENLFLNISALIALKMEKNELSTIMPGAFRNLGSLRYLSLANNKLRMLPIRV 120

  Fly   575 FTNSTNVDVIYLESNAIAHIDPNVFSTLVNLDHLYLRSNFIPLLPVTLFDKSTKLTSLSLDNNEI 639
            |.:..|::.:.|.:|.:..|.|..||...||..|.|..|.:..:|...||....||.|:|..|..
  Rat   121 FQDVNNLESLLLSNNQLVQIQPAQFSQFSNLRELQLHGNNLESIPEEAFDHLVGLTKLNLGRNSF 185

  Fly   640 QDLEIGMFRKLEHLREVRLHNNRIRRVRRGVFEPLPSLQELHIQKNSIEDIEPQAFHTLENMQHI 704
            ..|...:|:.|.:|:.:|||.||:..:..|.|:.|.:||||.:|:|.|..:.|..||...|:|.:
  Rat   186 THLSPRLFQHLGNLQVLRLHENRLSDIPMGTFDALGNLQELALQENQIGTLSPGLFHNNRNLQRL 250

  Fly   705 NLQDNQLTVLEDIFPDENSSLLSVQLEANYLHKVHPRTFSRQQKVQIMWLKDNQLTRVERSFFAD 769
            .|.:|.::.|.                        |..|.:..::..:.|..|.|..:....|..
  Rat   251 YLSNNHISQLP------------------------PGIFMQLPQLNKLTLFGNSLRELSPGVFGP 291

  Fly   770 TPQLGRLYLSDNKIRDIEKDTFVNLLLLQFLDLSGNQLRQLRRDYFAPLQDLEELSLARNHIEAI 834
            .|.|..|:|.:|.|..:..:||.:|..||.|.||.|||..:....|..|.:|.||||..|.::.:
  Rat   292 MPNLRELWLYNNHITSLADNTFSHLNQLQVLILSHNQLTYISPGAFNGLTNLRELSLHTNALQDL 356

  Fly   835 EGYAFAKLKNLKSLDLSHNPLVQLTRDIFSNEFPLNSLNLGNCSLRKLEQHAFKSLTNLNELNLE 899
            :...|..|.||:::.|..|.|.||...||:|...|.::.|.|.:|..|....|..|.||.||.|.
  Rat   357 DSNVFRSLANLQNISLQSNRLRQLPGSIFANVNGLTTIQLQNNNLENLPLGIFDHLVNLCELRLY 421

  Fly   900 RNQ---------------LNPADIQTLDIP------NLRRLLLSHNNFSYAG 930
            .|.               ||.|.:.|..:|      |:|...|...|.::.|
  Rat   422 DNPWRCDSDILPLHNWLLLNRARLGTDTLPVCSSPANVRGQSLVIININFPG 473

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42346NP_001036303.2 leucine-rich repeat 303..325 CDD:275380
LRR_8 325..384 CDD:290566
leucine-rich repeat 327..350 CDD:275380
leucine-rich repeat 351..461 CDD:275380
LRR_8 373..433 CDD:290566
LRR_RI 397..648 CDD:238064 42/137 (31%)
leucine-rich repeat 399..422 CDD:275380
leucine-rich repeat 462..485 CDD:275380
LRR_8 465..520 CDD:290566 3/8 (38%)
leucine-rich repeat 486..509 CDD:275380
LRR_8 508..567 CDD:290566 18/56 (32%)
leucine-rich repeat 510..533 CDD:275380 6/21 (29%)
LRR_RI 527..785 CDD:238064 75/258 (29%)
leucine-rich repeat 534..556 CDD:275380 8/22 (36%)
LRR_8 555..613 CDD:290566 18/57 (32%)
leucine-rich repeat 557..580 CDD:275380 7/22 (32%)
leucine-rich repeat 581..604 CDD:275380 6/22 (27%)
LRR_8 604..663 CDD:290566 21/58 (36%)
leucine-rich repeat 605..628 CDD:275380 7/22 (32%)
leucine-rich repeat 629..652 CDD:275380 8/22 (36%)
LRR_8 652..711 CDD:290566 23/58 (40%)
leucine-rich repeat 653..676 CDD:275380 9/22 (41%)
leucine-rich repeat 677..700 CDD:275380 10/22 (45%)
leucine-rich repeat 701..748 CDD:275380 6/46 (13%)
leucine-rich repeat 725..736 CDD:275378 0/10 (0%)
leucine-rich repeat 749..772 CDD:275380 4/22 (18%)
LRR_8 771..831 CDD:290566 25/59 (42%)
leucine-rich repeat 773..793 CDD:275380 7/19 (37%)
LRR_RI 804..1076 CDD:238064 46/148 (31%)
LRR_8 821..903 CDD:290566 31/96 (32%)
leucine-rich repeat 821..844 CDD:275380 8/22 (36%)
leucine-rich repeat 845..868 CDD:275380 9/22 (41%)
leucine-rich repeat 869..892 CDD:275380 7/22 (32%)
leucine-rich repeat 893..915 CDD:275380 10/42 (24%)
leucine-rich repeat 916..944 CDD:275380 4/15 (27%)
leucine-rich repeat 945..968 CDD:275380
LRR_8 967..1027 CDD:290566
leucine-rich repeat 969..992 CDD:275380
leucine-rich repeat 993..1014 CDD:275380
LRR_8 1015..1075 CDD:290566
leucine-rich repeat 1017..1040 CDD:275380
leucine-rich repeat 1041..1064 CDD:275380
LRR_RI <1047..1244 CDD:238064
LRR_8 1063..1125 CDD:290566
leucine-rich repeat 1089..1114 CDD:275380
leucine-rich repeat 1115..1162 CDD:275380
LRR_8 1163..1219 CDD:290566
leucine-rich repeat 1163..1186 CDD:275380
leucine-rich repeat 1187..1210 CDD:275380
leucine-rich repeat 1211..1233 CDD:275380
leucine-rich repeat 1234..1257 CDD:275380
LRR_8 1235..1292 CDD:290566
leucine-rich repeat 1258..1279 CDD:275380
leucine-rich repeat 1282..1306 CDD:275380
Lrrc15NP_659551.1 LRR_8 54..113 CDD:290566 18/56 (32%)
LRR 1 54..75 6/18 (33%)
LRR 2 78..99 6/20 (30%)
leucine-rich repeat 79..102 CDD:275380 8/22 (36%)
LRR_RI <94..303 CDD:238064 68/232 (29%)
LRR_8 102..161 CDD:290566 19/58 (33%)
LRR 3 102..123 7/20 (35%)
leucine-rich repeat 103..126 CDD:275380 7/22 (32%)
LRR 4 126..147 6/20 (30%)
leucine-rich repeat 127..150 CDD:275380 6/22 (27%)
LRR_8 149..209 CDD:290566 21/59 (36%)
LRR 5 150..171 7/20 (35%)
leucine-rich repeat 151..174 CDD:275380 7/22 (32%)
LRR 6 174..195 7/20 (35%)
leucine-rich repeat 175..198 CDD:275380 8/22 (36%)
LRR_8 198..257 CDD:290566 23/58 (40%)
LRR 7 198..219 8/20 (40%)
leucine-rich repeat 199..222 CDD:275380 9/22 (41%)
LRR 8 222..243 9/20 (45%)
leucine-rich repeat 223..246 CDD:275380 10/22 (45%)
LRR_8 245..305 CDD:290566 16/83 (19%)
LRR 9 246..267 7/44 (16%)
leucine-rich repeat 247..270 CDD:275380 6/46 (13%)
LRR 10 270..291 4/20 (20%)
leucine-rich repeat 271..294 CDD:275380 4/22 (18%)
LRR_8 293..353 CDD:290566 25/59 (42%)
LRR 11 294..315 7/20 (35%)
leucine-rich repeat 295..318 CDD:275380 8/22 (36%)
LRR_4 318..358 CDD:289563 16/39 (41%)
LRR 12 318..339 9/20 (45%)
leucine-rich repeat 319..342 CDD:275380 10/22 (45%)
LRR 13 342..363 7/20 (35%)
leucine-rich repeat 343..364 CDD:275380 7/20 (35%)
LRR_8 366..424 CDD:290566 22/57 (39%)
LRR 14 366..387 9/20 (45%)
leucine-rich repeat 367..387 CDD:275380 8/19 (42%)
LRR 15 390..411 6/20 (30%)
leucine-rich repeat 391..412 CDD:275380 6/20 (30%)
TPKR_C2 423..>462 CDD:301599 8/38 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 476..500
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - mtm9042
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR45617
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
44.010

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