DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG42346 and pan-1

DIOPT Version :9

Sequence 1:NP_001036303.2 Gene:CG42346 / 3355160 FlyBaseID:FBgn0259677 Length:1817 Species:Drosophila melanogaster
Sequence 2:NP_497925.1 Gene:pan-1 / 175596 WormBaseID:WBGene00003915 Length:594 Species:Caenorhabditis elegans


Alignment Length:528 Identity:129/528 - (24%)
Similarity:230/528 - (43%) Gaps:89/528 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   669 GVFEPLPSLQELHIQKNSIEDIEPQAFHTLENMQHIN--------LQDNQLTVL-EDIFPDENSS 724
            |:|..:... .:..:..||..:.       ||:..:|        ::|:.:.|| :|:|  ||..
 Worm    49 GIFSTVKGF-TIECESASIASVS-------ENLASLNGTELGRLTIRDSTVNVLPQDLF--ENVF 103

  Fly   725 LLSVQLEANYLHKVHPRTF-SRQQKVQIMWLKDNQLTRVERSFFADTPQLGRLYLSDNKIRDIEK 788
            ...|:||...|..:.|.:| |.....:::.|::|::.::|:..|.....|..|.|:.|||::|:.
 Worm   104 AKQVKLERCGLSTLQPNSFQSLGGSAELLSLRENRIKKLEKGLFTGLKSLKTLDLAMNKIQEIDV 168

  Fly   789 DTFVNLLLLQFLDLSGNQLRQLRRDYFAPLQDLEELSLARNHIEAIEGYAFAKLKNLKSLDLSHN 853
            ..|..|..::.|.|:.|.:|.|:...|..:::|::|:|...::|.|:..||..|.:|:.|.||:|
 Worm   169 GAFEELKKVEELLLNENDIRVLKTGTFDGMKNLKKLTLQNCNLEIIQKGAFRGLNSLEQLILSNN 233

  Fly   854 PLVQLTRDIFSNEFPLNSLNLGNCSLRKLEQHAFKSLTNLNELNLERNQLNP-ADIQTLDIPNLR 917
            .|..:...|||....|..|:||:..:..:|   .||...|.:|.|..|.::. ..|:..|:|:|.
 Worm   234 NLENIDWTIFSALKNLRVLDLGSNKISNVE---MKSFPKLEKLVLNNNTIDSMKSIKLKDLPSLV 295

  Fly   918 RLLLSHNNFSYAGSVGIMAGMLDRLRSLQQLSMSNCSLGQIPDLLFAKNTNLVRLDLCDNRL--- 979
            ..|...|.....|.:.:..  |.|...::.||::..:|.||....|....||:.|.|..|::   
 Worm   296 VALFDRNKIESIGDMDMFG--LTRSDRIETLSLARNNLSQISPKAFQHTPNLITLLLQYNQIEEL 358

  Fly   980 -----TQINRNIFSGLNVFKELRLCRNELS-----DFPHIALYNLSTLESLDLARNQLASIDFFK 1034
                 :|:.....:.|.....|:|..|.||     :.|       .:|.||.|..|.::.|:...
 Worm   359 SSHSPSQVRTPFLASLKKLVTLQLSSNNLSVIRSDELP-------KSLSSLALDHNVISKIEARA 416

  Fly  1035 LSGTLNLRQLILRDNKITAL--SGFNAVNLTQLDSVDLSGN---LLLSLPANFLRHSINLQKVHL 1094
            |.| :.:::|.|..||:..|  ..|::.:...:::||:|.|   .:.:.|..:|..       .|
 Worm   417 LEG-MEIKRLYLHSNKLNYLYQGTFDSFSPKSVEAVDVSLNPWVCVCNDPKEWLPR-------WL 473

  Fly  1095 SNNRFLQIPSSALSDVSIP------------------RLSWLNLTGNPINRIYTV---------- 1131
            ..:....:...||..::||                  |..|:.:... |..|.|:          
 Worm   474 EASEEADVAEGALGCLAIPNCGQKEGSTVMPEEEEVYRSGWITVAAT-ILTIVTIVIMVIIAMLY 537

  Fly  1132 -KEERYPY 1138
             |:.||.:
 Worm   538 FKDARYQF 545

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42346NP_001036303.2 leucine-rich repeat 303..325 CDD:275380
LRR_8 325..384 CDD:290566
leucine-rich repeat 327..350 CDD:275380
leucine-rich repeat 351..461 CDD:275380
LRR_8 373..433 CDD:290566
LRR_RI 397..648 CDD:238064
leucine-rich repeat 399..422 CDD:275380
leucine-rich repeat 462..485 CDD:275380
LRR_8 465..520 CDD:290566
leucine-rich repeat 486..509 CDD:275380
LRR_8 508..567 CDD:290566
leucine-rich repeat 510..533 CDD:275380
LRR_RI 527..785 CDD:238064 31/125 (25%)
leucine-rich repeat 534..556 CDD:275380
LRR_8 555..613 CDD:290566
leucine-rich repeat 557..580 CDD:275380
leucine-rich repeat 581..604 CDD:275380
LRR_8 604..663 CDD:290566
leucine-rich repeat 605..628 CDD:275380
leucine-rich repeat 629..652 CDD:275380
LRR_8 652..711 CDD:290566 8/49 (16%)
leucine-rich repeat 653..676 CDD:275380 2/6 (33%)
leucine-rich repeat 677..700 CDD:275380 2/22 (9%)
leucine-rich repeat 701..748 CDD:275380 15/56 (27%)
leucine-rich repeat 725..736 CDD:275378 3/10 (30%)
leucine-rich repeat 749..772 CDD:275380 4/22 (18%)
LRR_8 771..831 CDD:290566 18/59 (31%)
leucine-rich repeat 773..793 CDD:275380 8/19 (42%)
LRR_RI 804..1076 CDD:238064 78/290 (27%)
LRR_8 821..903 CDD:290566 28/81 (35%)
leucine-rich repeat 821..844 CDD:275380 8/22 (36%)
leucine-rich repeat 845..868 CDD:275380 9/22 (41%)
leucine-rich repeat 869..892 CDD:275380 7/22 (32%)
leucine-rich repeat 893..915 CDD:275380 6/22 (27%)
leucine-rich repeat 916..944 CDD:275380 6/27 (22%)
leucine-rich repeat 945..968 CDD:275380 6/22 (27%)
LRR_8 967..1027 CDD:290566 18/72 (25%)
leucine-rich repeat 969..992 CDD:275380 6/30 (20%)
leucine-rich repeat 993..1014 CDD:275380 6/25 (24%)
LRR_8 1015..1075 CDD:290566 18/64 (28%)
leucine-rich repeat 1017..1040 CDD:275380 8/22 (36%)
leucine-rich repeat 1041..1064 CDD:275380 6/24 (25%)
LRR_RI <1047..1244 CDD:238064 23/126 (18%)
LRR_8 1063..1125 CDD:290566 13/82 (16%)
leucine-rich repeat 1089..1114 CDD:275380 5/42 (12%)
leucine-rich repeat 1115..1162 CDD:275380 7/35 (20%)
LRR_8 1163..1219 CDD:290566
leucine-rich repeat 1163..1186 CDD:275380
leucine-rich repeat 1187..1210 CDD:275380
leucine-rich repeat 1211..1233 CDD:275380
leucine-rich repeat 1234..1257 CDD:275380
LRR_8 1235..1292 CDD:290566
leucine-rich repeat 1258..1279 CDD:275380
leucine-rich repeat 1282..1306 CDD:275380
pan-1NP_497925.1 leucine-rich repeat 130..152 CDD:275380 4/21 (19%)
LRR_8 132..187 CDD:290566 16/54 (30%)
leucine-rich repeat 153..176 CDD:275380 9/22 (41%)
leucine-rich repeat 177..200 CDD:275380 6/22 (27%)
LRR_8 199..259 CDD:290566 21/59 (36%)
leucine-rich repeat 201..224 CDD:275380 8/22 (36%)
LRR_RI 224..434 CDD:238064 60/222 (27%)
leucine-rich repeat 225..248 CDD:275380 9/22 (41%)
leucine-rich repeat 249..269 CDD:275380 7/22 (32%)
LRR_8 268..355 CDD:290566 24/88 (27%)
leucine-rich repeat 270..293 CDD:275380 6/22 (27%)
leucine-rich repeat 294..320 CDD:275380 6/27 (22%)
LRR_8 320..387 CDD:290566 16/66 (24%)
leucine-rich repeat 321..344 CDD:275380 6/22 (27%)
LRR_8 375..432 CDD:290566 17/64 (27%)
leucine-rich repeat 377..398 CDD:275380 6/27 (22%)
leucine-rich repeat 399..420 CDD:275380 8/21 (38%)
leucine-rich repeat 423..442 CDD:275380 6/18 (33%)
LRR_RI 80..326 CDD:238064 71/252 (28%)
leucine-rich repeat 81..104 CDD:275380 7/24 (29%)
leucine-rich repeat 105..128 CDD:275380 7/22 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR45617
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
22.010

Return to query results.
Submit another query.