DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Coa7 and SKT5

DIOPT Version :9

Sequence 1:NP_001036323.1 Gene:Coa7 / 3355158 FlyBaseID:FBgn0039965 Length:266 Species:Drosophila melanogaster
Sequence 2:NP_009492.1 Gene:SKT5 / 852218 SGDID:S000000157 Length:696 Species:Saccharomyces cerevisiae


Alignment Length:331 Identity:64/331 - (19%)
Similarity:109/331 - (32%) Gaps:104/331 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 DLKKE--SDVKEYVEKLGVE------------YRFGCYS--------------------EKKPEA 34
            |||.:  .:.:.|::||.::            |..|.:.                    |....|
Yeast   249 DLKLQFLKEAQSYLKKLSIKGYSDAQYLLADGYSSGAFGKIENKEAFVLFQAAAKHGHIESAYRA 313

  Fly    35 CHLLGDYLEGIKKDFEKASKVYKSTCDDYGYAKSCYKYGNYSFLGK-----------------GK 82
            .|.|.:.| |..:|..|:....|... ...:..:.||.|.|||.|:                 .:
Yeast   314 SHCLEEGL-GTTRDSRKSVNFLKFAA-SRNHPSAMYKLGLYSFYGRMGLPTDVNTKLNGVKWLSR 376

  Fly    83 SGSKGNPQVAYEYYEKGCNLNDSDACLHSGLLLVSKSMPREIDWNVPKGLEFLTKSCDLNNATAC 147
            :.::.|...|...||..       ...|.|.|.|  .:|.|     ...:|...::..|.:..:.
Yeast   377 AAARANELTAAAPYELA-------KIYHEGFLDV--VIPDE-----KYAMELYIQAASLGHVPSA 427

  Fly   148 FYLSGMHISGVQKKADQSAV-----TASSGSGTSSPPAG---------QPPLKDSDYIVLKDMKK 198
            ..|:.::.:|.......:::     |.::..|.|....|         :|..:       ||..:
Yeast   428 TLLAQIYETGNDTVGQDTSLSVHYYTQAALKGDSVAMLGLCAWYLLGAEPAFE-------KDENE 485

  Fly   199 AFQFAHKACELRNMYACANLSQMYARGDGIEKNEKEAEKYKKLALEMQDE--------------- 248
            |||:|.:|.......|...|...|..|.|.::|.:.|.|:.:.|...:|:               
Yeast   486 AFQWALRAANAGLPKAQFTLGYFYEHGKGCDRNMEYAWKWYEKAAGNEDKRAINKLRSRDGGLAS 550

  Fly   249 -VKKQH 253
             .||||
Yeast   551 IGKKQH 556

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Coa7NP_001036323.1 TPR <28..248 CDD:223861 51/270 (19%)
SLR repeat 48..78 CDD:276807 8/29 (28%)
SLR repeat 88..117 CDD:276807 7/28 (25%)
SLR repeat 127..156 CDD:276807 3/28 (11%)
SLR repeat 195..224 CDD:276807 9/28 (32%)
SEL1 214..247 CDD:214772 9/32 (28%)
SKT5NP_009492.1 TPR 245..505 CDD:223861 51/278 (18%)
SLR repeat 254..283 CDD:276807 4/28 (14%)
SLR repeat 290..319 CDD:276807 4/28 (14%)
SLR repeat 326..355 CDD:276807 8/29 (28%)
SLR repeat 407..436 CDD:276807 4/33 (12%)
SLR repeat 444..473 CDD:276807 4/28 (14%)
SLR repeat 482..511 CDD:276807 9/28 (32%)
SEL1 499..534 CDD:214772 9/34 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0790
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
32.770

Return to query results.
Submit another query.