Protein Alignment Coa7 and ACK1

DIOPT Version :10

• Sequence 1: NP_001036323.1
• Gene: Coa7 / 3355158
• FlyBaseID: FBgn0039965
• Length: 266
• Species: Drosophila melanogaster
• Sequence 2: NP_010078.1
• Gene: ACK1 / 851324
• SGDID: S000002362
• Length: 623
• Species: Saccharomyces cerevisiae
• Alignment Length: 247
• Identity: 54/247 - (21%)
• Similarity: 99/247 - (40%)
• Gaps: 64/247 - (25%)

  Fly     5 LKKESDVKEYVEKLGVEYRFGCYSE----KKPEACHLLGDYLEGIKKDFEKASKVYKSTCDDYGY 65
            ||.|..:|.  :|:.:|:.|...::    |.|.|.:|:|..
Yeast   289 LKPEEMLKN--QKVILEHSFKVLTKLITLKWPPAMYLMGTL------------------------ 327

  Fly    66 AKSCYKYGNYSFLG-KGKSGSKGNPQVAYEYYEKGCNLNDSDACLHSGLLLVSKSMPREIDWN-- 127
                  |.:..:|. |.|:....|.:.|.|||.|...||:||||..:|:....:.....:|.:
Yeast   328 ------YSHQPYLPIKNKNIVIKNDEKALEYYCKAAKLNNSDACYRAGVCFEYQRGTSSLDPSPT 386

  Fly   128 ----VPKGLEFLTKSCDLNNATACFYLSGM-HISGV-QKKADQSAVTASSGSGTSSPPAGQPPLK 186
                :.|..::.....::.:.:||.|..|| |:.|: .:|.|  .:.|......::.....|.
Yeast   387 KEQCIKKAFQYYQHGAEVCSNSACMYKLGMSHLYGLNMQKTD--VLLAIKWFDKAAQKGDSPQ-- 447

  Fly   187 DSDYIVLKDMKKAFQFAHKACELRNMYACANLSQMYARGDGIEKNEKEAEKY 238
                 .|.::.|.::|:....|::|:        ::|  :||.|:.:.|.||
Yeast   448 -----TLYELGKIYEFSVLPPEIQNL--------LFA--NGIRKDSQLAIKY 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Coa7	NP_001036323.1	TPR	<32..244	CDD:440553	46/216 (21%)
		SLR repeat	48..78	CDD:276807	1/29 (3%)
		SLR repeat	88..117	CDD:276807	13/28 (46%)
		SLR repeat	127..156	CDD:276807	7/35 (20%)
		SLR repeat	195..224	CDD:276807	4/28 (14%)
ACK1	NP_010078.1	SLR repeat	301..330	CDD:276807	8/58 (14%)
		SEL1	318..361	CDD:214772	15/72 (21%)
		SLR repeat	345..374	CDD:276807	13/28 (46%)
		SLR repeat	390..420	CDD:276807	7/29 (24%)
		TPR	<394..608	CDD:440553	23/110 (21%)
		SLR repeat	428..458	CDD:276807	5/38 (13%)
		SLR repeat	515..547	CDD:276807
		SLR repeat	556..588	CDD:276807