Protein Alignment Coa7 and COA7

DIOPT Version :10

• Sequence 1: NP_001036323.1
• Gene: Coa7 / 3355158
• FlyBaseID: FBgn0039965
• Length: 266
• Species: Drosophila melanogaster
• Sequence 2: NP_075565.2
• Gene: COA7 / 65260
• HGNCID: 25716
• Length: 231
• Species: Homo sapiens
• Alignment Length: 258
• Identity: 84/258 - (32%)
• Similarity: 130/258 - (50%)
• Gaps: 36/258 - (13%)

  Fly     4 DLKKESDVKEYVEKLGVEYRFGCYSEKKPEACHLLGDYLEGIKKDFEKASKVYKSTCDDYGYAKS 68
            |.:.|..||.::|.:.||..:.||.||.|:.|:.|.||||||:|:|::|:||.|..|::..::.|
Human     6 DFQDEEQVKSFLENMEVECNYHCYHEKDPDGCYRLVDYLEGIRKNFDEAAKVLKFNCEENQHSDS 70

  Fly    69 CYKYGNYSFLGKGKSGSKGNPQVAYEYYEKGC---NLNDSDACLHSGLLLVSKSMPREIDWNVPK 130
            |||.|.|...|||  |...:.:.|...:...|   ......||.:.|||.....:..:...::.|
Human    71 CYKLGAYYVTGKG--GLTQDLKAAARCFLMACEKPGKKSIAACHNVGLLAHDGQVNEDGQPDLGK 133

  Fly   131 GLEFLTKSCDLNNATACFYLSGMHISGVQKKADQSAVTASSGSGTSSPPAGQPPLKDSDYIVLKD 195
            ..::.|::||....::||.||.|.:.|.                     .|.|          ||
Human   134 ARDYYTRACDGGYTSSCFNLSAMFLQGA---------------------PGFP----------KD 167

  Fly   196 MKKAFQFAHKACELRNMYACANLSQMYARGDGIEKNEKEAEKYKKLALEMQDEVKKQHDTLGF 258
            |..|.:::.|||:|.:::||||.|:||..|||::|:|.:||..|..|.::..|.:|....|.|
Human   168 MDLACKYSMKACDLGHIWACANASRMYKLGDGVDKDEAKAEVLKNRAQQLHKEQQKGVQPLTF 230

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Coa7	NP_001036323.1	TPR	<32..244	CDD:440553	69/214 (32%)
		SLR repeat	48..78	CDD:276807	12/29 (41%)
		SLR repeat	88..117	CDD:276807	7/31 (23%)
		SLR repeat	127..156	CDD:276807	9/28 (32%)
		SLR repeat	195..224	CDD:276807	14/28 (50%)
COA7	NP_075565.2	TPR	<21..214	CDD:440553	74/225 (33%)
		Sel1-like 1	34..66		16/31 (52%)
		SLR repeat	50..80	CDD:276807	12/29 (41%)
		Sel1-like 2	68..104		12/37 (32%)
		SLR repeat	88..120	CDD:276807	7/31 (23%)
		Sel1-like 3	108..146		9/37 (24%)
		SLR repeat	130..159	CDD:276807	9/28 (32%)
		Sel1-like 4	147..183		16/66 (24%)
		Sel1-like 5	184..219		16/34 (47%)