DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Coa7 and chr3

DIOPT Version :9

Sequence 1:	NP_001036323.1	Gene:	Coa7 / 3355158	FlyBaseID:	FBgn0039965	Length:	266	Species:	Drosophila melanogaster
Sequence 2:	NP_592847.1	Gene:	chr3 / 2541607	PomBaseID:	SPAC24B11.10c	Length:	932	Species:	Schizosaccharomyces pombe

Alignment Length:	276	Identity:	56/276 - (20%)
Similarity:	95/276 - (34%)	Gaps:	98/276 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 YDLKKESDVKEYVEKLGVEYRFGCYSEKK---------PEACHLLGDYLEGIKKDFEKASKVYKS 58
            |....|.||.|.:.::.:.|..|...:|:         ..||...|.  |.::..:|.| |:|:.
pombe   702 YKKAAEMDVVEAMFRIALIYLNGLLGQKRNISLGVQWLERACKSKGP--ESVRAMYELA-KIYEQ 763

  Fly    59 TCDDYGYAKSCYKYGNYSFLGKGKSGSKGNPQVAYEYYEKG---------CNLNDSDACLHSGLL 114
            . |.||.:                    ..|:..:|.|::.         |.|.:   |...|||
pombe   764 P-DRYGVS--------------------ATPERKFELYKQSAVYGYAAAQCKLGE---CYEHGLL 804

  Fly   115 LVSKSMPREIDWNVPKGLEFLTKSCDLNNATACFYLSGMHISGVQKKADQSAVTASSGSGTSSPP 179
            .......|.|.|        .|::.:.:...|...|||.:::|
pombe   805 GCLAEPRRSIFW--------YTRAAEQDYGEAELGLSGWYLTG---------------------- 839

  Fly   180 AGQPPLKDSDYIVLKDMKKAFQFAHKACELRNMYACANLSQ-------MYARGDGIEKNEKEAEK 237
                    |:.|:.|:.::|..:||||       ||..|::       |..:|.|:..:...|..
pombe   840 --------SEGILPKNGEEALLWAHKA-------ACKGLAKAQYAVGFMMEQGIGVAADPSSAHN 889

  Fly   238 -YKKLALEMQDEVKKQ 252
             |.:.|.:...:.||:
pombe   890 WYIRAAKQGFPKAKKR 905

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Coa7	NP_001036323.1	TPR	<28..248	CDD:223861	47/245 (19%)
		SLR repeat	48..78	CDD:276807	7/29 (24%)
		SLR repeat	88..117	CDD:276807	9/37 (24%)
		SLR repeat	127..156	CDD:276807	5/28 (18%)
		SLR repeat	195..224	CDD:276807	9/35 (26%)
		SEL1	214..247	CDD:214772	9/40 (23%)
chr3	NP_592847.1	TPR	617..925	CDD:223861	56/276 (20%)
		SLR repeat	619..650	CDD:276807
		SEL1	638..674	CDD:214772
		SLR repeat	658..687	CDD:276807
		Sel1	675..709	CDD:285450	2/6 (33%)
		SLR repeat	694..723	CDD:276807	6/20 (30%)
		Sel1	711..744	CDD:285450	5/32 (16%)
		SLR repeat	731..763	CDD:276807	8/34 (24%)
		SLR repeat	774..801	CDD:276807	5/29 (17%)
		Sel1	789..825	CDD:285450	10/46 (22%)
		SLR repeat	809..838	CDD:276807	8/36 (22%)
		SLR repeat	847..876	CDD:276807	9/35 (26%)
		SEL1	864..898	CDD:214772	6/33 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0790
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.860