DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Coa7 and chr1

DIOPT Version :9

Sequence 1:	NP_001036323.1	Gene:	Coa7 / 3355158	FlyBaseID:	FBgn0039965	Length:	266	Species:	Drosophila melanogaster
Sequence 2:	NP_596099.1	Gene:	chr1 / 2540265	PomBaseID:	SPBC3E7.12c	Length:	456	Species:	Schizosaccharomyces pombe

Alignment Length:	191	Identity:	42/191 - (21%)
Similarity:	82/191 - (42%)	Gaps:	12/191 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAYDLKKESDVKEYVEKLGVEYRFGCYSEKKPEACHLLGDYLE--GIKKDFEKASKVYKSTCDDY 63
            :|...||:.:::..:|.|  ||.....:.::....:.|.:..:  |..:|.:....:|.... ..
pombe   264 LAIKAKKDGNLENAIEFL--EYIMPEVASQQNFVPYELAELYKQRGTSQDLKSILPLYMLAA-SL 325

  Fly    64 GYAKSCYKYGNYSFLGKGKSGSKGNPQVAYEYYEKGCNLNDSDACLHSGLLLVSKSMPREIDWNV 128
            |:.:|.:..|...|.  |..|::.|...|.:||....:..::||.| :...|..:.:|..|..:.
pombe   326 GHDRSSFLVGEAFFY--GTYGARENKLRALQYYHLANDKGNADAML-ALCKLYLRGLPGHIFPSS 387

  Fly   129 PKGLEFLTKSCDLNNATACFYLSGMHISGVQKKADQSAVTASSGSGTSSPPAGQPPLKDSD 189
            .:..|:..::..|.:|.||:.|...:.:||....|    .|.|.:|..:......|:.|:|
pombe   388 RRAFEYAHRAAMLGHAPACYVLGKFYETGVGCVKD----LAKSEAGFRAGLINDSPITDAD 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Coa7	NP_001036323.1	TPR	<28..248	CDD:223861	35/164 (21%)
		SLR repeat	48..78	CDD:276807	5/29 (17%)
		SLR repeat	88..117	CDD:276807	8/28 (29%)
		SLR repeat	127..156	CDD:276807	6/28 (21%)
		SLR repeat	195..224	CDD:276807
		SEL1	214..247	CDD:214772
chr1	NP_596099.1	TPR	262..>426	CDD:223861	37/171 (22%)
		SLR repeat	273..305	CDD:276807	5/33 (15%)
		SLR repeat	311..340	CDD:276807	5/29 (17%)
		SLR repeat	347..377	CDD:276807	8/30 (27%)
		Sel1	365..402	CDD:285450	8/37 (22%)
		SLR repeat	386..415	CDD:276807	6/28 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0790
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.770