Protein Alignment Coa7 and Sel1l

DIOPT Version :10

• Sequence 1: NP_001036323.1
• Gene: Coa7 / 3355158
• FlyBaseID: FBgn0039965
• Length: 266
• Species: Drosophila melanogaster
• Sequence 2: NP_001034178.1
• Gene: Sel1l / 20338
• MGIID: 1329016
• Length: 790
• Species: Mus musculus
• Alignment Length: 191
• Identity: 44/191 - (23%)
• Similarity: 74/191 - (38%)
• Gaps: 50/191 - (26%)

  Fly    75 YSFLGK----------------GKSGSKGNPQVAYEYYEKGCNLNDSDACLHSGLLLVSKS--MP 121
            |.||.:                |..|.:.|.|.|::|:....|..:|.|....|.:....|  :|
Mouse   360 YQFLAEKGDVQAQVGLGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHAMAFLGKMYSEGSDIVP 424

  Fly   122 REIDWNVPKGLEFLTKSCDLNN-------ATACFYLSGMHIS------GVQKKADQSAVTASSGS 173
            :..:    ..|.:..|:.|:.|       ..|..|..|:.::      ..||.|:|..|.
Mouse   425 QSNE----TALHYFKKAADMGNPVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQGWVD----- 480

  Fly   174 GTSSPPAGQPPLKDSDYI---VLKDMKKAFQFAHKACELRNMYACANLSQMYARGDGIEKN 231
                   ||..|....|.   |.:|.|:|.::.:.|.:..::.|..||:||:|.|.|:.::
Mouse   481 -------GQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGHILAFYNLAQMHASGTGVMRS 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Coa7	NP_001036323.1	TPR	<32..244	CDD:440553	44/191 (23%)
		SLR repeat	48..78	CDD:276807	1/2 (50%)
		SLR repeat	88..117	CDD:276807	8/28 (29%)
		SLR repeat	127..156	CDD:276807	7/35 (20%)
		SLR repeat	195..224	CDD:276807	9/28 (32%)
Sel1l	NP_001034178.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	22..51
		Interaction with ERLEC1, OS9 and SYVN1. /evidence=ECO:0000250	23..733		44/191 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	67..98
		FN2	116..164	CDD:128373
		SLR repeat	201..227	CDD:276807
		SLR repeat	234..263	CDD:276807
		SEL1	251..286	CDD:214772
		SLR repeat	270..299	CDD:276807
		Important for homodimerization and oligomerization. /evidence=ECO:0000269|PubMed:27064360	348..533		44/188 (23%)
		TPR	<359..548	CDD:440553	44/191 (23%)
		SLR repeat	389..418	CDD:276807	8/28 (29%)
		SLR repeat	426..455	CDD:276807	5/32 (16%)
		SLR repeat	462..491	CDD:276807	8/40 (20%)
		SLR repeat	566..595	CDD:276807
		SLR repeat	602..635	CDD:276807
		SEL1	625..658	CDD:214772
		Interaction with SYVN1. /evidence=ECO:0000269|PubMed:27064360	639..719
		SLR repeat	642..672	CDD:276807
		Sel1	660..693	CDD:429881
		Mediates retention in the endoplasmic reticulum. /evidence=ECO:0000250	734..790
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	763..790