DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Coa7 and coa-7

DIOPT Version :9

Sequence 1:	NP_001036323.1	Gene:	Coa7 / 3355158	FlyBaseID:	FBgn0039965	Length:	266	Species:	Drosophila melanogaster
Sequence 2:	NP_496487.1	Gene:	coa-7 / 174784	WormBaseID:	WBGene00013925	Length:	249	Species:	Caenorhabditis elegans

Alignment Length:	258	Identity:	81/258 - (31%)
Similarity:	138/258 - (53%)	Gaps:	24/258 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LKKESDVKEYVEKLGVEYRFGCYSEKKPEACHLLGDYLEGIKKDFEKASKVYKSTCDDYGYAKSC 69
            ::::::..|||:.:|:|||||||.||:||:|.|||:|:|.::::|:.|..::|..||:..|.|||
Worm    10 MQEQAERAEYVKNIGIEYRFGCYEEKRPESCQLLGEYMEALQQNFQAAVAIFKKNCDENSYPKSC 74

  Fly    70 YKYGNYSFLGKGKSGSKGNPQVAYEYYEKGCNLNDSDACLHSGLLLVSKSMPREIDWNVPKGLEF 134
            :|||.|..  .||.|...:........:..|:.|....|.:..|:..:....|:.|  ..|...:
Worm    75 FKYGMYML--AGKVGDDASLSKMIRPMKIACDANIPQGCRYLSLVHWNGEKDRKAD--SEKAERY 135

  Fly   135 LTKSCDLNNATACFYLSGMHISGVQKKADQSAVTASSGSGTSSPPAGQPPLKDSDYIVL----KD 195
            :.::|:|.:..||:.||..::...:|....:|..|                |:.|...|    :|
Worm   136 MRRACELEDGEACWLLSTWYMGNKEKFKTNAAGEA----------------KELDRAELGSLSRD 184

  Fly   196 MKKAFQFAHKACELRNMYACANLSQMYARGDGIEKNEKEAEKYKKLALEMQDEVKKQHDTLGF 258
            |.|:.|||.:|||:....:|||:|:|:..|||:.|:..:|:||...|.|:.:.::......||
Worm   185 MDKSLQFAIRACEMDIPQSCANVSRMFKLGDGVPKDLDQAKKYADRAKEIMETLRSNDTNAGF 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Coa7	NP_001036323.1	TPR	<28..248	CDD:223861	68/223 (30%)
		SLR repeat	48..78	CDD:276807	13/29 (45%)
		SLR repeat	88..117	CDD:276807	4/28 (14%)
		SLR repeat	127..156	CDD:276807	7/28 (25%)
		SLR repeat	195..224	CDD:276807	14/28 (50%)
		SEL1	214..247	CDD:214772	14/32 (44%)
coa-7	NP_496487.1	TPR	48..>231	CDD:223861	57/202 (28%)
		SLR repeat	53..83	CDD:276807	13/31 (42%)
		SLR repeat	128..156	CDD:276807	8/29 (28%)
		SLR repeat	184..213	CDD:276807	14/28 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156345
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11317
Inparanoid	1	1.050	150	1.000	Inparanoid score	I2973
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58643
OrthoDB	1	1.010	-	-		D1341787at2759
OrthoFinder	1	1.000	-	-		FOG0007049
OrthoInspector	1	1.000	-	-		oto17198
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR13891
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2791
SonicParanoid	1	1.000	-	-		X5134
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.040