Protein Alignment scro and BARX2

DIOPT Version :10

• Sequence 1: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_003649.2
• Gene: BARX2 / 8538
• HGNCID: 956
• Length: 279
• Species: Homo sapiens
• Alignment Length: 284
• Identity: 71/284 - (25%)
• Similarity: 116/284 - (40%)
• Gaps: 67/284 - (23%)

  Fly    85 HHHHNLSSIHHLQNLHSQHQSTLFNSNHSTPFSVTDILSPIEES---YRKLELNGNPPS------ 140
            |....|||...|:....::::          |.:.:|||  :|:   :.||.|....||
Human     4 HAELRLSSPGQLKAARRRYKT----------FMIDEILS--KETCDYFEKLSLYSVCPSLVVRPK 56

  Fly   141 PFRSNSSSSSINSPGTLTTSTMANPYAMGTLYHSPGVQTYCGPTDNLSLAGHYTDMRNSASWYGS 205
            |..|.:.|.|:.:...|:..|.........:..:||:..        :|:.|......||...|.
Human    57 PLHSCTGSPSLRAYPLLSVITRQPTVISHLVPATPGIAQ--------ALSCHQVTEAVSAEAPGG 113

  Fly   206 TANDPRFAISRLMSSSASGTMSHMGNMSGLAACSVSDSKPLQFPLAQRRKRRVLFTQAQVYELER 270
            .|          ::||.|.|               ....|.|   .:.|:.|.:||:.|:..||:
Human   114 EA----------LASSESET---------------EQPTPRQ---KKPRRSRTIFTELQLMGLEK 150

  Fly   271 RFKQQRYLSAPEREHLASLIHLTPTQVKIWFQNHRYKCKRQAKEKAMAEQNQHNQPASSPRRVAV 335
            :|::|:|||.|:|..||..:.||..|||.|:||.|.|.|:...:   ..|....:|...|::.::
Human   151 KFQKQKYLSTPDRLDLAQSLGLTQLQVKTWYQNRRMKWKKMVLK---GGQEAPTKPKGRPKKNSI 212

  Fly   336 PV---LVKDGKPCSGNNSSSQSQQ 356
            |.   :..:.|    .||.:|.|:
Human   213 PTSEEIEAEEK----MNSQAQGQE 232

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeodomain	254..310	CDD:459649	26/55 (47%)
BARX2	NP_003649.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	110..137		9/54 (17%)
		Homeodomain	134..190	CDD:459649	26/55 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..279		9/46 (20%)