Protein Alignment scro and nkx2.1

DIOPT Version :10

• Sequence 1: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_571851.1
• Gene: nkx2.1 / 81883
• ZFINID: ZDB-GENE-010404-1
• Length: 346
• Species: Danio rerio
• Alignment Length: 349
• Identity: 153/349 - (43%)
• Similarity: 202/349 - (57%)
• Gaps: 41/349 - (11%)

  Fly   112 HSTPFSVTDILSPIEESYRKLELNGN----PPSPFRSNSSSSS------INSPGTLTTSTMANPY 166
            |:|||||:|||||:||||:|:.:.||    |.:.:|....:.:      :...||:..:......
Zfish     7 HTTPFSVSDILSPLEESYKKVSMEGNNLGAPLASYRQPQVTQAAMQQHHMGHNGTVPAAYHMTAA 71

  Fly   167 AMGTLYHSPGVQTYC-GPTDNLSLAGHYTD-MRNS---ASWYGSTANDPRFA-ISRLMSSSASGT 225
            .:..|.|: .:..|| |...|:|....|.| ||.|   .|||| |..||||: |||.|.||:.
Zfish    72 GVSQLSHT-AMGGYCNGNLGNMSDLPAYQDGMRGSTTATSWYG-TNPDPRFSTISRFMGSSSG-- 132

  Fly   226 MSHMGNMSGLAACSVSDSKPLQFPLAQ--RRKRRVLFTQAQVYELERRFKQQRYLSAPEREHLAS 288
             .:||:||.|:  |::|......||..  ||||||||:||||||||||||||:||||||||||||
Zfish   133 -MNMGSMSTLS--SLADVGKGMGPLTSTPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLAS 194

  Fly   289 LIHLTPTQVKIWFQNHRYKCKRQAKEKAMAEQNQHN-----QPASSPRRVAVPVLVKDGKPCSGN 348
            :||||||||||||||||||.|||||:|...:|.|.:     |...|||||||||||||||||.|:
Zfish   195 MIHLTPTQVKIWFQNHRYKMKRQAKDKVSQQQMQQDNGSCQQQQQSPRRVAVPVLVKDGKPCQGS 259

  Fly   349 ----NSSSQSQQHGTNSTSAGNNTGSANNGNANSGIVSVTANVSGGLNLITGDAPNSHSPDTSSS 409
                |:..|:..|...:.....||..:.:.:.:..:.|...::..|.:..:..:..:..|..|.
Zfish   260 SHTPNTGVQNHHHQGGNVMFMTNTSLSMSQHQSQQVGSAGQSLDLGQHAASPPSLQTQVPGLSH- 323

  Fly   410 LLASYGTVGGSNVAMLQQPCNNTL 433
             |.|.|:..|:.:     ||:..|
Zfish   324 -LNSSGSEYGAAL-----PCSALL 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeodomain	254..310	CDD:459649	51/55 (93%)
nkx2.1	NP_571851.1	Homeodomain	160..216	CDD:459649	51/55 (93%)