DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment scro and Nkx6-3

DIOPT Version :9

Sequence 1:	NP_001015473.1	Gene:	scro / 3355151	FlyBaseID:	FBgn0287186	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	NP_001102925.1	Gene:	Nkx6-3 / 685102	RGDID:	1597780	Length:	262	Species:	Rattus norvegicus

Alignment Length:	255	Identity:	66/255 - (25%)
Similarity:	103/255 - (40%)	Gaps:	84/255 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 TPFSVTDILS-PIEESYRKLELNGNPPSPFRSNSSSSSINSPGTLTTSTMANPYAMGTLYHSPGV 177
            ||..:||||| |:......| |:|.|     ..:....::|.|               :|:.|.|
  Rat    51 TPHGITDILSRPVATPNSSL-LSGYP-----HVAGFGGLSSQG---------------VYYGPQV 94

  Fly   178 QTYCGPTDNLSLAGHYTDMRN-----SASWYGSTANDPRFAISRLMSSSASGTMSHMGNMSGLAA 237
            .:: ..|.|    .:.|..||     ...|.|||                             ..
  Rat    95 GSF-SKTGN----EYPTRTRNCWADTGQDWRGST-----------------------------RP 125

  Fly   238 CSVSDSKPLQFPLAQRRKRRVLFTQAQVYELERRFKQQRYLSAPEREHLASLIHLTPTQVKIWFQ 302
            || :...||...:.:::..|..||..|::.||:.|:|.:||:.|||..||..:.:|.:|||:|||
  Rat   126 CS-NTPDPLSDTIHKKKHTRPTFTGHQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQ 189

  Fly   303 NHRYKCKRQAKEKAMAEQNQHNQPASSPRRVAVPVLVKDGKP--CSGNNSSSQSQQHGTN 360
            |.|.|.:   |:.|:       :|:||..|.          |  .||:.::|:::....|
  Rat   190 NRRTKWR---KKSAL-------EPSSSTPRA----------PGGASGDRAASENEDDEYN 229

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeobox	256..309	CDD:278475	25/52 (48%)
Nkx6-3	NP_001102925.1	Homeobox	143..197	CDD:395001	25/56 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336884
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840