Protein Alignment scro and NKX3-2

DIOPT Version :9

• Sequence 1: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_001180.1
• Gene: NKX3-2 / 579
• HGNCID: 951
• Length: 333
• Species: Homo sapiens
• Alignment Length: 309
• Identity: 95/309 - (30%)
• Similarity: 123/309 - (39%)
• Gaps: 103/309 - (33%)

  Fly   110 SNHSTPFSVTDILSPIEESYRKLELNGNPPSPFRSNSSSSSINSPGTLTTSTMANPY-------- 166
            :|..|.||:..||:..||........|.|              :||....|..|.|.
Human     6 ANTLTSFSIQAILNKKEERGGLAAPEGRP--------------APGGTAASVAAAPAVCCWRLFG 56

  Fly   167 -----AMG----TLYHSP-GVQTYCGPT------------------------------------D 185
                 |:|    :|..|| |.:|..|.|                                    .
Human    57 ERDAGALGGAEDSLLASPAGTRTAAGRTAESPEGWDSDSALSEENESRRRCADARGASGAGLAGG 121

  Fly   186 NLSL----------------AGHYTDMRNSASWYGS----TAND---PRFAISRLMSSSASGTMS 227
            :|||                |...:|...|||..|.    |.:|   ||.|....:.|.|.|
Human   122 SLSLGQPVCELAASKDLEEEAAGRSDSEMSASVSGDRSPRTEDDGVGPRGAHVSALCSGAGG--- 183

  Fly   228 HMGNMSGLAACSVSDSKPLQFPLAQRRKRRVLFTQAQVYELERRFKQQRYLSAPEREHLASLIHL 292
              |..||.|..:..:.:|.. |..::::.|..|:.|||:||||||..|||||.|||..||:.:.|
Human   184 --GGGSGPAGVAEEEEEPAA-PKPRKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKL 245

  Fly   293 TPTQVKIWFQNHRYKCKRQAKEKAMAEQNQHNQPASSPRRVAVPVLVKD 341
            |.|||||||||.|||.||    :.||.....:.||:  ::|||.|||:|
Human   246 TETQVKIWFQNRRYKTKR----RQMAADLLASAPAA--KKVAVKVLVRD 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeobox	256..309	CDD:278475	35/52 (67%)
NKX3-2	NP_001180.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	65..113		7/47 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	138..212		21/79 (27%)
		Homeobox	209..262	CDD:278475	35/52 (67%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143174
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0842
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740