Protein Alignment scro and nkx6.2

DIOPT Version :10

• Sequence 1: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_001129256.1
• Gene: nkx6.2 / 565782
• ZFINID: ZDB-GENE-070626-1
• Length: 278
• Species: Danio rerio
• Alignment Length: 334
• Identity: 88/334 - (26%)
• Similarity: 129/334 - (38%)
• Gaps: 109/334 - (32%)

  Fly    63 KLNTNETSTQNTVSTAAAAAVAHHHHNLSSI------HHLQNLHSQHQSTLFNSNH----STPFS 117
            ::::|..|.....||..||.     ||::.:      :.||:.......:|.|.|.    .||..
Zfish     6 QMDSNRQSAFVLGSTPLAAL-----HNMTEMKTSLFPYALQSPAGFKAPSLGNLNSQIPLGTPHG 65

  Fly   118 VTDILS-PIEESYRKLELNGNPPSPFRSNSSSSSINSPGTLTTSTMANPYAMGTLYHSPGVQTYC 181
            ::|||. ||..:.:.  |:|.|           .||.   |.||.       |..::...|..|
Zfish    66 ISDILGRPITTAGQL--LSGFP-----------RING---LATSA-------GMYFNPAAVSRY- 106

  Fly   182 GPTDNLSLAGHYTDMRNSASW----YGSTANDPRFAISRLMSSSASGTMSHMGNMSGLAACSVSD 242
             |.....|.|     |....|    .||...|||      :..:|...|  |.:..|
Zfish   107 -PKPLTELPG-----RAPIFWPGMMQGSPWRDPR------VPCAAQANM--MLDKDG-------- 149

  Fly   243 SKPLQFPLAQRRKRRVLFTQAQVYELERRFKQQRYLSAPEREHLASLIHLTPTQVKIWFQNHRYK 307
                     :::..|..|:..|::.||:.|:|.:||:.|||..||..:.:|.:|||:||||.|.|
Zfish   150 ---------KKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTK 205

  Fly   308 C-KRQAKEKAMA------------------EQNQHNQPA---SSPRRVAVPVLVKDGK------- 343
            . ||.|.|.|.|                  |.:::|:|.   |...::.  .|:|..|
Zfish   206 WRKRHAAEMATAKKKHDSETEKMKESSDNDEDDEYNKPLDPNSDDEKIT--RLLKKHKTSNLSLL 268

  Fly   344 -PCSGNNSS 351
             |||  |||
Zfish   269 SPCS--NSS 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeodomain	254..310	CDD:459649	24/56 (43%)
nkx6.2	NP_001129256.1	Homeodomain	150..208	CDD:459649	24/57 (42%)