Protein Alignment scro and NKX2-2

DIOPT Version :9

• Sequence 1: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_002500.1
• Gene: NKX2-2 / 4821
• HGNCID: 7835
• Length: 273
• Species: Homo sapiens
• Alignment Length: 286
• Identity: 106/286 - (37%)
• Similarity: 130/286 - (45%)
• Gaps: 83/286 - (29%)

  Fly   110 SNHSTPFSVTDIL--------------SPIEESYRKLELNGNPPSPFRSNSSSSSINSPGTLTTS 160
            :|..|.|||.|||              .|.||:        ..|.|                  :
Human     4 TNTKTGFSVKDILDLPDTNDEEGSVAEGPEEEN--------EGPEP------------------A 42

  Fly   161 TMANPYAMGTLYHSPGVQTYCGPTDNLSLAGHYTDMRNS--ASWYGSTANDPRFAISRLMSSSAS 223
            ..|.|...|.|   ..||       :|.|...:.|..::  ..|..|| ...::::..|   :|.
Human    43 KRAGPLGQGAL---DAVQ-------SLPLKNPFYDSSDNPYTRWLAST-EGLQYSLHGL---AAG 93

  Fly   224 GTMSHMGNMSGLAACSVSDSKPLQFP-----LAQRRKRRVLFTQAQVYELERRFKQQRYLSAPER 283
            .......:.|...:...|.....:.|     ..::|||||||::||.|||||||:||||||||||
Human    94 APPQDSSSKSPEPSADESPDNDKETPGGGGDAGKKRKRRVLFSKAQTYELERRFRQQRYLSAPER 158

  Fly   284 EHLASLIHLTPTQVKIWFQNHRYKCKRQAKEKAMAEQNQHNQPASSPRRVAVPVLVKDGKPCSGN 348
            |||||||.||||||||||||||||.||     |.||:.....|..|||||||||||:|||||...
Human   159 EHLASLIRLTPTQVKIWFQNHRYKMKR-----ARAEKGMEVTPLPSPRRVAVPVLVRDGKPCHAL 218

  Fly   349 NS-----------------SSQSQQH 357
            .:                 |:||.||
Human   219 KAQDLAAATFQAGIPFSAYSAQSLQH 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeobox	256..309	CDD:278475	47/52 (90%)
NKX2-2	NP_002500.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..56		17/80 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	90..131		6/43 (14%)
		Homeobox	131..185	CDD:395001	47/53 (89%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143179
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0842
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X524
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.740