Protein Alignment scro and DBX2

DIOPT Version :10

• Sequence 1: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_001004329.2
• Gene: DBX2 / 440097
• HGNCID: 33186
• Length: 339
• Species: Homo sapiens
• Alignment Length: 321
• Identity: 78/321 - (24%)
• Similarity: 114/321 - (35%)
• Gaps: 101/321 - (31%)

  Fly   138 PPSPFRSNSSSSSINSPGTLTTSTMANPYAMGTLYHSPGVQTYCGPTDNLSLAGHYTDMRNSASW 202
            ||:|          :.|.|...:..|.   :..|..||.....|...:.:|.||         :.
Human    56 PPAP----------HDPATALATAGAQ---LRPLPASPVPLKLCPAAEQVSPAG---------AP 98

  Fly   203 YGSTANDPRFAISRLMSSSASGTMSHMGNMSGLAACSVSDSKP---------------------- 245
            ||:     |:|...|..|:.|..:.  |...|...|:...|.|
Human    99 YGT-----RWAFQVLSPSADSARLP--GRAPGDRDCTFQPSAPAPSKPFLLSTPPFYSACCGGSC 156

  Fly   246 ------LQFP--------LAQ------RR--KRRVLFTQAQVYELERRFKQQRYLSAPEREHLAS 288
                  ..||        |.|      ||  .||.:|::.|...||:.|::|:|:|..:|:.||.
Human   157 RRPASSTAFPREESMLPLLTQDSNSKARRGILRRAVFSEDQRKALEKMFQKQKYISKTDRKKLAI 221

  Fly   289 LIHLTPTQVKIWFQNHRYKCKRQAKEK------AMAEQNQHNQPASSPRRVAVPVLVKDGKPCSG 347
            .:.|..:||||||||.|.|. |.:|||      .:.|......|.|   |.|:      |.|...
Human   222 NLGLKESQVKIWFQNRRMKW-RNSKEKEVLSNRCIQEVGLQEDPLS---RSAL------GFPSPC 276

  Fly   348 NNSSSQSQQHGT-----NSTSAGNNTGSANNG----NANS---GIVSVTANVSGGLNLITG 396
            .:.....|||.:     ||..........::|    .|||   .:...:...:|...::||
Human   277 PSIWDVPQQHSSPRWRENSPEPSERLIQESSGAPPPEANSLQGALYLCSEEEAGSKGVLTG 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeodomain	254..310	CDD:459649	25/57 (44%)
DBX2	NP_001004329.2	PRK12323	<3..>146	CDD:481241	25/118 (21%)
		Homeodomain	189..243	CDD:459649	24/54 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	282..318		9/35 (26%)