Protein Alignment scro and Hmx

DIOPT Version :10

• Sequence 1: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_001262674.1
• Gene: Hmx / 42110
• FlyBaseID: FBgn0264005
• Length: 718
• Species: Drosophila melanogaster
• Alignment Length: 557
• Identity: 127/557 - (22%)
• Similarity: 185/557 - (33%)
• Gaps: 180/557 - (32%)

  Fly     3 SHGLAYTTRIERKSYRELQINRDQYFVTAPNEEDLVMSLSPK---------DTLIHTAISQHHQV 58
            :||..:...::.......|..:.|..|...:::..|..|||.         |.:      |.|.:
  Fly   117 AHGATHPALLQHALTPTGQQQQQQLQVQQQHQQSHVERLSPPMKSPERNGGDEV------QGHSL 175

  Fly    59 --DTSTKLNTNETSTQNTVSTAAAAAVAHHHHNLSSIHHLQNLHSQHQSTLFNSNHSTPFSVTDI 121
              :.|..||.|.|......:.||||..|.:..|.|:..:..:.....:||. .||..|.||::.|
  Fly   176 NNNNSKALNHNNTCASAAAAAAAAAVAAANLSNNSNDSNGSSGGGGGKSTT-GSNGFTSFSISSI 239

  Fly   122 LSPIEESYRKLELNG-------------------------------------------------- 136
            ||..|.:.:    ||
  Fly   240 LSRSEPAKK----NGAAGLITPIPQLPQPGAGGPQDAAMLSRLGFISQWGALAGRYAALCPPGWP 300

  Fly   137 ----------------------NPPSPFRSNSSSSSINSPGTLTTSTMANP----YAMGTLYHSP 175
                                  ||||| .|.|.:::.|:..|..:|..|:.    :.:..|||..
  Fly   301 WAPQRLPFHSPTHDSSSTNTTENPPSP-TSMSPNNNNNNSNTTASSNQASKSPSHHPLHPLYHPL 364

  Fly   176 GVQTYCGPTDNLSLAGHYTDMRNSASWYGSTANDPRFAISRLMSSSASG------------TMSH 228
            |.|     ........|....:............|....:...|||:.|            |.||
  Fly   365 GSQ-----QQQQQQQQHQQHPQQQQHPQQQQQQHPHQPTTPTSSSSSGGGSSLTHHPHPHLTGSH 424

  Fly   229 MGNM-------------------SGLAACSVSDSKPLQFPLAQRRKRRVLFTQAQVYELERRFKQ 274
            .|.:                   .|....|.|.|........:::|.|.:|::|||::||..|..
  Fly   425 GGYLLPSSSNESDEEGEEIIEEDDGTDGPSDSSSPHGDGNSKRKKKTRTVFSRAQVFQLESTFDL 489

  Fly   275 QRYLSAPEREHLASLIHLTPTQVKIWFQNHRYKCKRQAKEKAMAEQNQHNQPASSPRRVAVPVLV 339
            :||||:.||..||:.:.||.|||||||||.|.|.|||...:..| .|..|...::.|.|.||||.
  Fly   490 KRYLSSSERAGLAASLRLTETQVKIWFQNRRNKWKRQLAAELEA-ANMANMAHAAQRLVRVPVLY 553

  Fly   340 KDGKPCSGNNSSSQSQQHGTNSTSAGNNTGSANNGNANSGIVSVTANVSGGLNLITGDAPNSHSP 404
            .|| ..:|.........|.....:|..||                                  ||
  Fly   554 HDG-TTAGFVPPPPPHHHPMQYYAAARNT----------------------------------SP 583

  Fly   405 DTS--SSLLASYGTVGGSNVAMLQQPCNNTLMSNSLA 439
            ...  |||: ..|.:..:.:::|:.|       ||:|
  Fly   584 PRPPLSSLVXGVGCLATAPMSLLKPP-------NSMA 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeodomain	254..310	CDD:459649	30/55 (55%)
Hmx	NP_001262674.1	Homeodomain	469..525	CDD:459649	30/55 (55%)