Protein Alignment scro and Nkx2-4

DIOPT Version :9

• Sequence 1: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: XP_038962557.1
• Gene: Nkx2-4 / 366213
• RGDID: 1304985
• Length: 353
• Species: Rattus norvegicus
• Alignment Length: 347
• Identity: 150/347 - (43%)
• Similarity: 192/347 - (55%)
• Gaps: 65/347 - (18%)

  Fly   112 HSTPFSVTDILSPIEESYRKL--ELNGNPP---SPFRSNSSSSSINSPGTLTTST--MANPYAM- 168
            |:|||||:||||||||:|:|.  .::|.||   :|..:.:..:....|.:...:.  |..|:||
  Rat     7 HTTPFSVSDILSPIEETYKKFGGVMDGAPPGLGAPLGAAAYRAPPTGPSSQAAAVAGMQPPHAMA 71

  Fly   169 -----------------GTLYH-SPGVQ--------TYC-GPTDNLSLAGHYTD-MRNSAS---- 201
                             ...|| .|||.        :|| |...|:.....||| ||..|:
  Rat    72 GHNAAAAAAAAAAAAAAAATYHMPPGVSQFPHSAMGSYCNGGLGNMGELPAYTDGMRGGAAAAAT 136

  Fly   202 -WYGSTANDPRF-AISRLMSSSASGTMSHMGNMSGLAACSVSDSKPLQFPLAQRRKRRVLFTQAQ 264
             |||:. .|||: :|||.|..||...::.||:::|:|..:.| ..||. ..|.||||||||:|||
  Rat   137 GWYGAN-TDPRYSSISRFMGPSAGVNVAGMGSLTGIADAAKS-LAPLH-AAAPRRKRRVLFSQAQ 198

  Fly   265 VYELERRFKQQRYLSAPEREHLASLIHLTPTQVKIWFQNHRYKCKRQAKEKAMAEQNQHN----- 324
            |||||||||||:||||||||||||:||||||||||||||||||.|||||:||..:..|..
  Rat   199 VYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQLQQEGGLGPP 263

  Fly   325 --QPASSPRRVAVPVLVKDGKPC---SGNNSSSQSQQHGTNSTSAGNNTGSANN-------GNAN 377
              .|..|||||||||||||||||   :|..:..|..|.....|.|......:::       |...
  Rat   264 PPPPPPSPRRVAVPVLVKDGKPCQNGAGTPTPGQGGQQPQAPTPASELEELSSSPPALHGPGGGL 328

  Fly   378 SGIVSVTANVSGGL---NLITG 396
            :.:.:.|.:..||:   ||:.|
  Rat   329 AALDTATGDYGGGVLGANLLYG 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeobox	256..309	CDD:278475	49/52 (94%)
Nkx2-4	XP_038962557.1	Homeobox	190..244	CDD:395001	49/53 (92%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	114	1.000	Domainoid score	I5913
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H41526
Inparanoid	1	1.050	218	1.000	Inparanoid score	I3494
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1348801at2759
OrthoFinder	1	1.000	-	-		FOG0002967
OrthoInspector	1	1.000	-	-		otm45980
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR24340
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X524
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	10.070