Protein Alignment scro and Hlx

DIOPT Version :10

• Sequence 1: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_001071142.1
• Gene: Hlx / 364069
• RGDID: 1311961
• Length: 476
• Species: Rattus norvegicus
• Alignment Length: 460
• Identity: 109/460 - (23%)
• Similarity: 182/460 - (39%)
• Gaps: 123/460 - (26%)

  Fly    78 AAAAAVAHHHHNLSSIHHLQNLHSQHQSTLFNSNHSTP-FSVTDI-------LSPIEESY----- 129
            |:||..||    |.|:|.    |:..|:...:....|| .:.:::       |||:..:|
  Rat    67 ASAALTAH----LGSVHP----HASFQAAARSPLRPTPVVAPSEVPAGFPQRLSPLSAAYHQHLP 123

  Fly   130 -----RKLELNGNPPSPFRSNSSSSSINSPGTLTTSTMANPYAMG-------------------- 169
                 ::.:....||.|.|    :.|:..|   |:.|...|:..|
  Rat   124 QQPPTQQQQPQQQPPPPPR----AGSLQPP---TSGTRVVPHHSGSAPAPSSKDLKFGIDRILSA 181

  Fly   170 ----------TLYHSPGVQTYCGPTDNLSLAGHYTDMRNSASWYGSTANDP---RFAISRLMSSS 221
                      ||.....:.|...|| .:.|||    ::.||..:.::. ||   ..||...:||:
  Rat   182 EFDPKVKEGNTLRDLTSLLTGGRPT-GVHLAG----LQPSAGQFFASL-DPISEASAILSPLSSN 240

  Fly   222 ASGTMSH--MGNMSGLAACSVSDSKPLQFPLAQRRKR---RVLFTQAQVYELERRFKQQRYLSAP 281
            ...::.|  .....|..|....|:.|..:    :|||   |.:|:..|...||:||:.|:|::.|
  Rat   241 PRNSVQHQFQDTFPGPYAVLTKDTMPQTY----KRKRSWSRAVFSNLQRKGLEKRFEIQKYVTKP 301

  Fly   282 EREHLASLIHLTPTQVKIWFQNHRYKCK-------RQAKEKAMAEQNQHNQPASSPRRVAVPVLV 339
            :|:.||:::.||..|||:||||.|.|.:       ::.|:|...|:.....||...|....|...
  Rat   302 DRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKEAQAQKDKDKEAGEKPSGGVPAEGEREERSPSRS 366

  Fly   340 KDGKPCSGNNSSS----QSQQHGTNSTSAGNNTGSANNGNANSGIVSVTANVSGGLNLITGDAPN 400
            :.......::|.|    .|....|..|....:..:....:|...:::.:::.||          :
  Rat   367 EGEAESESSDSESLDMAPSDTERTEGTERSLHQTTVIKASAAGALITASSSASG----------S 421

  Fly   401 SHSPDTSSSLLASYGTVG-----GSNVAMLQQPCNNTLMSNSLAMAYRNQNNFISNGHQQQCGGY 460
            |.|..:||||.:|.|:.|     |||       |:..|.|:..:         :::|.|......
  Rat   422 SFSFSSSSSLGSSNGSAGSASSLGSN-------CSELLPSHQPS---------VTSGPQSPEIAQ 470

  Fly   461 LPLQG 465
            :||.|
  Rat   471 VPLAG 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeodomain	254..310	CDD:459649	27/65 (42%)
Hlx	NP_001071142.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	121..170		10/55 (18%)
		Homeodomain	270..330	CDD:459649	27/59 (46%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	328..401		12/72 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	413..476		22/89 (25%)