Protein Alignment scro and HOXC11

DIOPT Version :10

• Sequence 1: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_055027.1
• Gene: HOXC11 / 3227
• HGNCID: 5123
• Length: 304
• Species: Homo sapiens
• Alignment Length: 240
• Identity: 64/240 - (26%)
• Similarity: 102/240 - (42%)
• Gaps: 38/240 - (15%)

  Fly    85 HHHHNLSSIHHLQNLHSQHQSTLFNSNHSTPFSVTDILSPIEESYRKLELNGNPPSPFRSNSS-S 148
            ||.::.||.:...: ...|:..|      .|.:||:||...|.||..   :.:|.:|..:.:. .
Human    84 HHRNSYSSCYAAAD-ELMHRECL------PPSTVTEILMKNEGSYGG---HHHPSAPHATPAGFY 138

  Fly   149 SSINSPGTLTTSTMANPYAMGTLYHSPGVQTYCGPTDNLSLAGHYTDMRNSASWYGSTANDPRF- 212
            ||:|....|       |.|....:.:    .|||..|        .......|..|....:|..
Human   139 SSVNKNSVL-------PQAFDRFFDN----AYCGGGD--------PPAEPPCSGKGEAKGEPEAP 184

  Fly   213 AISRLMSSSASGTMSHM------GNMSGLAACSVSDSKPLQFPLAQR-RKRRVLFTQAQVYELER 270
            ..|.|.|.:.:|..:..      .:.||.|.....:......|.|.| ||:|..:::.|:.||||
Human   185 PASGLASRAEAGAEAEAEEENTNPSSSGSAHSVAKEPAKGAAPNAPRTRKKRCPYSKFQIRELER 249

  Fly   271 RFKQQRYLSAPEREHLASLIHLTPTQVKIWFQNHRYKCKRQAKEK 315
            .|....|::..:|..|:.:::||..||||||||.|.|.|:.::::
Human   250 EFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLSRDR 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeodomain	254..310	CDD:459649	24/55 (44%)
HOXC11	NP_055027.1	DUF3528	42..161	CDD:432284	23/97 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	166..237		15/70 (21%)
		Homeodomain	233..289	CDD:459649	24/55 (44%)