Protein Alignment scro and HOXC8

DIOPT Version :10

• Sequence 1: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_073149.1
• Gene: HOXC8 / 3224
• HGNCID: 5129
• Length: 242
• Species: Homo sapiens
• Alignment Length: 247
• Identity: 54/247 - (21%)
• Similarity: 84/247 - (34%)
• Gaps: 84/247 - (34%)

  Fly    94 HHLQNLHSQHQSTLFNSNHSTPFSVTDILSPIEESYRKLELNGNPPSPFRSNSSSSSINSPGTLT 158
            ||:|:......|.:.||.                              ::.|..|.|.:...:..
Human    54 HHVQDFFHHGTSGISNSG------------------------------YQQNPCSLSCHGDASKF 88

  Fly   159 TSTMANPYAMGTLYHSPGVQTYCGPTDNLSLAGHYTDMRNSASWYGSTANDPRFAISRLMSSSAS 223
            ....|.|.           |:..|.....|:. .|.|.::||:                 ::|:.
Human    89 YGYEALPR-----------QSLYGAQQEASVV-QYPDCKSSAN-----------------TNSSE 124

  Fly   224 GTMSHMGNMSGLAACSVSDSKPLQFPLAQ-----RRKRRVLFTQAQVYELERRFKQQRYLSAPER 283
            | ..|:...|         |..|.||..:     ||..|..:::.|..|||:.|....||:...|
Human   125 G-QGHLNQNS---------SPSLMFPWMRPHAPGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRR 179

  Fly   284 EHLASLIHLTPTQVKIWFQNHRYKCKRQ----------AKEKAMAEQNQHNQ 325
            ..::..:.||..||||||||.|.|.|::          .:||...|.|:..:
Human   180 IEVSHALGLTERQVKIWFQNRRMKWKKENNKDKLPGARDEEKVEEEGNEEEE 231

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeodomain	254..310	CDD:459649	22/55 (40%)
HOXC8	NP_073149.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	114..154		12/66 (18%)
		Antp-type hexapeptide	138..143		2/4 (50%)
		Homeodomain	150..206	CDD:459649	22/55 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	206..242		4/26 (15%)