Protein Alignment scro and HOXC6

DIOPT Version :10

• Sequence 1: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_004494.1
• Gene: HOXC6 / 3223
• HGNCID: 5128
• Length: 235
• Species: Homo sapiens
• Alignment Length: 221
• Identity: 58/221 - (26%)
• Similarity: 93/221 - (42%)
• Gaps: 39/221 - (17%)

  Fly   109 NSNHSTPFSVTDILSPIEESYRKLELNGNPPSPFRSNSS-----------SSSINSP-GTLTTST 161
            ||..:.| |::..|:..::....:.||.....|.|..|:           |:...|| ..:..|:
Human     2 NSYFTNP-SLSCHLAGGQDVLPNVALNSTAYDPVRHFSTYGAAVAQNRIYSTPFYSPQENVVFSS 65

  Fly   162 MANPYAMG--TLYHSPGVQTYCGPTDNLSLAGHYTD---MRNSASWYGSTANDPRFAISRLMSSS 221
            ...||..|  :.|....:.:.|    ..:..||.|.   .::.:|..|.||...:.|     |..
Human    66 SRGPYDYGSNSFYQEKDMLSNC----RQNTLGHNTQTSIAQDFSSEQGRTAPQDQKA-----SIQ 121

  Fly   222 ASGTMSHMGNMSGLAACSVSDSKPLQFPLAQRRKRRVLFTQAQVYELERRFKQQRYLSAPEREHL 286
            ....|..|.:.||:...            |.||:.|.::::.|..|||:.|...|||:...|..:
Human   122 IYPWMQRMNSHSGVGYG------------ADRRRGRQIYSRYQTLELEKEFHFNRYLTRRRRIEI 174

  Fly   287 ASLIHLTPTQVKIWFQNHRYKCKRQA 312
            |:.:.||..|:||||||.|.|.|:::
Human   175 ANALCLTERQIKIWFQNRRMKWKKES 200

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeodomain	254..310	CDD:459649	23/55 (42%)
HOXC6	NP_004494.1	Antp-type hexapeptide	122..127		0/4 (0%)
		Homeodomain	142..198	CDD:459649	23/55 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	200..235		0/1 (0%)