Protein Alignment scro and HOXC4

DIOPT Version :10

• Sequence 1: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_055435.2
• Gene: HOXC4 / 3221
• HGNCID: 5126
• Length: 264
• Species: Homo sapiens
• Alignment Length: 309
• Identity: 67/309 - (21%)
• Similarity: 107/309 - (34%)
• Gaps: 113/309 - (36%)

  Fly   105 STLFNSNHSTP-------FSVTDIL---SPIEESYRKLELNG--------NPPSPFRSN-----S 146
            |.|.:||:..|       :|....:   ||  |.|.:...:|        .||.|.|.:     .
Human     5 SYLMDSNYIDPKFPPCEEYSQNSYIPEHSP--EYYGRTRESGFQHHHQELYPPPPPRPSYPERQY 67

  Fly   147 SSSSINSPGTLTTSTMANPYAMGTLYHSPGVQTYCGPTDNLSLAGHYTDMRNSASWYGSTANDPR 211
            |.:|:..||    ::..:..|....:|....|:.|.|
Human    68 SCTSLQGPG----NSRGHGPAQAGHHHPEKSQSLCEP---------------------------- 100

  Fly   212 FAISRLMSSSASGTMSHMGNMSGLAAC---------SVSDSKPLQFPLAQR-------------- 253
               :.|..:|||.:.:.       .||         |.:..:|:.:|..::
Human   101 ---APLSGASASPSPAP-------PACSQPAPDHPSSAASKQPIVYPWMKKIHVSTVNPNYNGGE 155

  Fly   254 -RKRRVLFTQAQVYELERRFKQQRYLSAPEREHLASLIHLTPTQVKIWFQNHRYKCKRQAKEKAM 317
             ::.|..:|:.||.|||:.|...|||:...|..:|..:.|:..|:||||||.|.|.|:
Human   156 PKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKK------- 213

  Fly   318 AEQNQHNQP----ASSPRRVAVPVLVKDGKPCSGNNSSSQSQQHGTNST 362
                .|..|    .|:|...|.|..:....|       ..|:.|..::|
Human   214 ----DHRLPNTKVRSAPPAGAAPSTLSAATP-------GTSEDHSQSAT 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeodomain	254..310	CDD:459649	23/55 (42%)
HOXC4	NP_055435.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	19..130		26/154 (17%)
		Antp-type hexapeptide	135..140		1/4 (25%)
		Homeodomain	157..213	CDD:459649	23/55 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..264		10/45 (22%)