Protein Alignment scro and HOXB8

DIOPT Version :10

• Sequence 1: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_076921.1
• Gene: HOXB8 / 3218
• HGNCID: 5119
• Length: 243
• Species: Homo sapiens
• Alignment Length: 267
• Identity: 68/267 - (25%)
• Similarity: 96/267 - (35%)
• Gaps: 77/267 - (28%)

  Fly   133 ELNGNP-----PSPFRSNSSSSSI----NSPGTLTTST-MANPYAMGTLYHSPGVQTYCGPTDNL 187
            :|.|.|     ||...|....|.|    :.|.:|:|:. ..||.|: ..:..||......|....
Human    31 DLGGRPTVVYGPSSGGSFQHPSQIQEFYHGPSSLSTAPYQQNPCAV-ACHGDPGNFYGYDPLQRQ 94

  Fly   188 SLAGHYTDMRNSASWYGSTANDP---RFAISRLMSSSASGTMSHMGNMSGLAACSVSDSKPLQ-F 248
            ||.|               |.||   ::|..:|.::|..|..         |..|.....|.| |
Human    95 SLFG---------------AQDPDLVQYADCKLAAASGLGEE---------AEGSEQSPSPTQLF 135

  Fly   249 P------LAQRRKRRVLFTQAQVYELERRFKQQRYLSAPEREHLASLIHLTPTQVKIWFQNHRYK 307
            |      .|.||:.|..:::.|..|||:.|....||:...|..::..:.||..||||||||.|.|
Human   136 PWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMK 200

  Fly   308 CKRQAKEKAMAEQNQHNQPASSPRRVAVPVLVKDGKPCSGNNSSSQSQQHGTNSTSAGNNTGSAN 372
            .|:        |.|:...|:|.               |.......|..:....         :|:
Human   201 WKK--------ENNKDKFPSSK---------------CEQEELEKQKLERAPE---------AAD 233

  Fly   373 NGNANSG 379
            .|:|..|
Human   234 EGDAQKG 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeodomain	254..310	CDD:459649	22/55 (40%)
HOXB8	NP_076921.1	Antp-type hexapeptide	134..139		2/4 (50%)
		Homeodomain	147..203	CDD:459649	22/55 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	203..243		10/70 (14%)