Protein Alignment scro and Nkx2-3

DIOPT Version :10

• Sequence 1: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_001101064.1
• Gene: Nkx2-3 / 309389
• RGDID: 1308521
• Length: 362
• Species: Rattus norvegicus
• Alignment Length: 403
• Identity: 130/403 - (32%)
• Similarity: 175/403 - (43%)
• Gaps: 96/403 - (23%)

  Fly   113 STPFSVTDILSPIEE------SYRKLELNGNPPSPFRSNSSSSSINSPGTLTTSTMANPYAMGTL 171
            ||||||.|||: :|:      ::.:.||..:..|            :|..|..       |.||.
  Rat     9 STPFSVKDILN-LEQQRHFHGAHLQAELEQHLHS------------APCMLAA-------AEGTQ 53

  Fly   172 YHSPGVQTYCGPTDNLSLAGHYTDMRNSASWYGSTANDPRFAISRLMSSSASGTMSH-------- 228
            :...|.:......:.||    |.:...:|..:|.:...|:..:..::..|.||....
  Rat    54 FSDAGEEDEEEEGEKLS----YLNSLAAAEGHGVSGLCPQSYVHTVLRDSCSGPKEQEEEVVSER 114

  Fly   229 -------MGNMSGLAACSVSDS----KPLQFPLAQRRKRRVLFTQAQVYELERRFKQQRYLSAPE 282
                   ..::.....|..|:.    ||     ..|||.||||:||||:||||||||||||||||
  Rat   115 SQKSCQLKKSLEAAGDCKASEDGERPKP-----RSRRKPRVLFSQAQVFELERRFKQQRYLSAPE 174

  Fly   283 REHLASLIHLTPTQVKIWFQNHRYKCKRQAKEKAMAEQNQHNQPASSPRRVAVPVLVKDGKPCSG 347
            ||||||.:.||.|||||||||.|||||||.::|:: |...| .|...||||||||||:|||||..
  Rat   175 REHLASSLKLTSTQVKIWFQNRRYKCKRQRQDKSL-ELGTH-APPPPPRRVAVPVLVRDGKPCVT 237

  Fly   348 NNSSSQSQQHGTNSTSAGNNTGSANNGNANSGIVSVTANVSGGLNLITGDAPNSHSPDTSSSLLA 412
            .::.:....:|..:.:...|:..| .|..||...:..|..:..               .:::...
  Rat   238 PSAQAYGSPYGVGAGAYSYNSFPA-YGYGNSAAAAAAAAAAAA---------------AAAAYSG 286

  Fly   413 SYGTV-------GGSNVA-----MLQQPCNNTLMSNSLAMAYRNQNNFISNG-----HQQQCGGY 460
            |||..       ||...|     .:|..|:.|  .....:...|...|.|.|     ||....|.
  Rat   287 SYGCAYPTGGGGGGGGAASAATTAMQPACSAT--GGGSFVNVGNLGGFGSGGGAQPLHQGAAAGA 349

  Fly   461 LPLQG-----RAW 468
            ...||     |||
  Rat   350 ACAQGTLQGIRAW 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeodomain	254..310	CDD:459649	47/55 (85%)
Nkx2-3	NP_001101064.1	Homeodomain	146..202	CDD:459649	47/55 (85%)