Protein Alignment scro and VENTX

DIOPT Version :10

• Sequence 1: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_055283.1
• Gene: VENTX / 27287
• HGNCID: 13639
• Length: 258
• Species: Homo sapiens
• Alignment Length: 283
• Identity: 69/283 - (24%)
• Similarity: 105/283 - (37%)
• Gaps: 84/283 - (29%)

  Fly   132 LELNGNPPSPFRSNSSSSSINSPGTLTTSTMANP--------YAMGTLYHSPGVQTYCGPTDNLS 188
            :.|:.:||   |.....||..|...|:.|:.:.|        :::|:|   ||.    |.|
Human     1 MRLSSSPP---RGPQQLSSFGSVDWLSQSSCSGPTHTPRPADFSLGSL---PGP----GQT---- 51

  Fly   189 LAGHYTDMRNSASWYGSTANDPRFAISRLMSSSASGTMSHMGNMSGLAACSVSDSKPLQFPLAQR 253
                            |.|.:|..|:|...::.:|...:....|:||:    .:...|:.|
Human    52 ----------------SGAREPPQAVSIKEAAGSSNLPAPERTMAGLS----KEPNTLRAP---- 92

  Fly   254 RKRRVLFTQAQVYELERRFKQQRYLSAPEREHLASLIHLTPTQVKIWFQNHRYKCKRQAKEKAMA 318
             :.|..||..||..||..|:..:|||..||:.||..:.|:..|:|.||||.|.|.|||.::..:.
Human    93 -RVRTAFTMEQVRTLEGVFQHHQYLSPLERKRLAREMQLSEVQIKTWFQNRRMKHKRQMQDPQLH 156

  Fly   319 EQ---NQHNQPA---------------------SSPRRVAVP-------------VLVKDGKPCS 346
            ..   :.|..||                     |.|:.:.:|             .|...|..|.
Human   157 SPFSGSLHAPPAFYSTSSGLANGLQLLCPWAPLSGPQALMLPPGSFWGLCQVAQEALASAGASCC 221

  Fly   347 GNNSSSQSQQHGTNSTSAGNNTG 369
            |...:|.....|..|.....:||
Human   222 GQPLASHPPTPGRPSLGPALSTG 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeodomain	254..310	CDD:459649	24/55 (44%)
VENTX	NP_055283.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..93		27/130 (21%)
		Homeodomain	93..148	CDD:459649	24/54 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	227..248		5/18 (28%)