Protein Alignment scro and tlx1

DIOPT Version :10

• Sequence 1: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_739571.1
• Gene: tlx1 / 266964
• ZFINID: ZDB-GENE-021021-2
• Length: 301
• Species: Danio rerio
• Alignment Length: 326
• Identity: 79/326 - (24%)
• Similarity: 127/326 - (38%)
• Gaps: 92/326 - (28%)

  Fly    94 HHLQNLHSQHQSTLFNSNHSTPFSVTDILSPIEESYRKLELNGNPPSPFRSNSSSSSINSP---- 154
            |...:||..|..|:       .|.:..||:                   .::..|..|.:|
Zfish     3 HMGAHLHQTHADTI-------SFGIDQILN-------------------NADQGSCMITNPRMQD 41

  Fly   155 -----GTLTTSTMANPYAMGTLYHSPGVQTYCGPTDNLSLAGHYTDMRNSASWYGSTAND----- 209
                 |.:.::      |..|:..:..|....|...|....|.| :|...|:..|:..|.
Zfish    42 LDYGLGCIVST------AYNTMTGNYNVNNSSGYNGNSCSVGSY-NMNLGANVNGNCLNSSGVIR 99

  Fly   210 -----PRFAISRLMSSSAS-----GTMSHMGNMSGL------------------AACSVSDSKPL 246
                 |..::...:.:||:     |:|..:.|::||                  |....:.::.:
Zfish   100 VPAHRPLGSVHSSIPTSAATVPSMGSMGTINNLTGLTFPWMESNRRYTKDRFTVALSPFTVTRRI 164

  Fly   247 QFPLAQR-----RKRRVLFTQAQVYELERRFKQQRYLSAPEREHLASLIHLTPTQVKIWFQNHRY 306
            ..|...|     :|.|..||:.|:.|||:||.:|:||::.||..||..:.:|..|||.||||.|.
Zfish   165 GHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKTWFQNRRT 229

  Fly   307 KCKRQAKEKAMAEQNQHN------QPASSPRRVAVPVLVKDGKPCSGNNSS---SQSQQHGTNST 362
            |.:||..|:..||:.|.|      |..:..:.:..||   ...|...:|||   .|:.|..|.:|
Zfish   230 KWRRQTAEEREAERQQANRILMQLQQEAFQKTINQPV---TPDPICLHNSSLFALQNLQPWTENT 291

  Fly   363 S 363
            :
Zfish   292 A 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeodomain	254..310	CDD:459649	27/55 (49%)
tlx1	NP_739571.1	Homeodomain	177..233	CDD:459649	27/55 (49%)