DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment scro and NKX2-8

DIOPT Version :9

Sequence 1:NP_001015473.1 Gene:scro / 3355151 FlyBaseID:FBgn0287186 Length:468 Species:Drosophila melanogaster
Sequence 2:NP_055175.2 Gene:NKX2-8 / 26257 HGNCID:16364 Length:239 Species:Homo sapiens


Alignment Length:120 Identity:69/120 - (57%)
Similarity:80/120 - (66%) Gaps:15/120 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly   241 SDSKPLQFPLA------QRRKRRVLFTQAQVYELERRFKQQRYLSAPEREHLASLIHLTPTQVKI 299
            |..:|...|.:      :|:||||||::||..||||||:|||||||||||.||||:.||||||||
Human    66 SSQRPSARPASPGSDAEKRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKI 130

  Fly   300 WFQNHRYKCKRQAKEKAMAEQ-------NQHNQPASSPRRVAVPVLVKDGKPCSG 347
            ||||||||.|| |:....||.       ..|..|... |||.|||||:||:||.|
Human   131 WFQNHRYKLKR-ARAPGAAESPDLAASAELHAAPGLL-RRVVVPVLVRDGQPCGG 183

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
scroNP_001015473.1 Homeobox 256..309 CDD:278475 44/52 (85%)
NKX2-8NP_055175.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..87 4/20 (20%)
Homeobox 87..140 CDD:278475 44/52 (85%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165143169
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0842
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.740

Return to query results.
Submit another query.