Protein Alignment scro and Nkx2-4

DIOPT Version :9

• Sequence 1: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_075993.1
• Gene: Nkx2-4 / 228731
• MGIID: 97349
• Length: 354
• Species: Mus musculus
• Alignment Length: 358
• Identity: 154/358 - (43%)
• Similarity: 189/358 - (52%)
• Gaps: 86/358 - (24%)

  Fly   112 HSTPFSVTDILSPIEESYRKL--ELNGNPP--------SPFRSNSSSSSINSPGTLTTSTMANPY 166
            |:|||||:||||||||:|:|.  .::|.||        :.:|:..|..|  |......:.|..|:
Mouse     7 HTTPFSVSDILSPIEETYKKFGGVMDGAPPGLGAPLGAAAYRAPPSGPS--SQAAAVAAGMQPPH 69

  Fly   167 AM------------------GTLYH-SPGVQ--------TYC-GPTDNLSLAGHYTD-MRNSAS- 201
            ||                  ...|| .|||.        :|| |...|:.....||| ||..|:
Mouse    70 AMAGHNAAAAAAAAAAAAAAAATYHMPPGVSQFPHSAMGSYCNGGLGNMGELPAYTDGMRGGAAA 134

  Fly   202 ----WYGSTANDPRF-AISRLMSSSASGTMSHMGNMSGLAACSVSDSKPLQFPLAQRRKRRVLFT 261
                |||:. .|||: :|||.|..||...::.||:::|:|..:.| ..||. ..|.||||||||:
Mouse   135 AATGWYGAN-TDPRYSSISRFMGPSAGVNVAGMGSLTGIADAAKS-LAPLH-AAAPRRKRRVLFS 196

  Fly   262 QAQVYELERRFKQQRYLSAPEREHLASLIHLTPTQVKIWFQNHRYKCKRQAKEKAMAEQNQHN-- 324
            ||||||||||||||:||||||||||||:||||||||||||||||||.|||||:||..:..|..
Mouse   197 QAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQLQQEGGL 261

  Fly   325 -----QPASSPRRVAVPVLVKDGKPC---SGNNSSSQSQQHGTNSTSA--------------GNN 367
                 .|..|||||||||||||||||   :|..:..|..|.....|.|              |..
Mouse   262 GPPPPPPPPSPRRVAVPVLVKDGKPCQNGAGTPTPGQGGQQPQAPTPAPELEELSPSPPALHGPG 326

  Fly   368 TG----SANNGNANSGIVSVTANVSGGLNLITG 396
            .|    .|..|:...|::        |.||:.|
Mouse   327 GGLAALDAATGDYGGGVL--------GANLLYG 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeobox	256..309	CDD:278475	49/52 (94%)
Nkx2-4	NP_075993.1	Homeobox	191..244	CDD:278475	49/52 (94%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	245..329		31/83 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833332
Domainoid	1	1.000	114	1.000	Domainoid score	I6067
eggNOG	1	0.900	-	-		E2759_KOG0842
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H41526
Inparanoid	1	1.050	220	1.000	Inparanoid score	I3550
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002967
OrthoInspector	1	1.000	-	-		otm43892
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR24340
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2571
SonicParanoid	1	1.000	-	-		X524
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.880