DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment scro and R03G8.3

DIOPT Version :9

Sequence 1:	NP_001015473.1	Gene:	scro / 3355151	FlyBaseID:	FBgn0287186	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	NP_510174.3	Gene:	R03G8.3 / 181437	WormBaseID:	WBGene00010998	Length:	654	Species:	Caenorhabditis elegans

Alignment Length:	181	Identity:	38/181 - (20%)
Similarity:	60/181 - (33%)	Gaps:	49/181 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 YFVTAPNEEDLVMSLSPKDTLIHTAISQHHQVDTSTKLNTNETSTQNTVSTAAAAAVAHHHHN-- 89
            |..|.|   |::.:.......:...|.|.::...|||     :.|...|..|.|.||.:....
Worm   501 YIRTQP---DILRNCRNMPIPMQYCICQFNKTQVSTK-----SETAKGVGEAVALAVNNEIEEGK 557

  Fly    90 ------LSSIHHLQNLHSQHQ----STLFNSNHSTPFSVTDILSPIEESYR---KLELNGNPP-- 139
                  ...:.|:.:|....|    |.|:.       :|.::..|.:..|:   |:..||...
Worm   558 FTDKCVKMKVDHVVSLLQFDQKFKGSMLYT-------AVVEMTKPSKAVYKANVKILENGEVKVL 615

  Fly   140 -SPFRSNSSSSSINSPGTLTTSTMANPYAMGTLYHSPGVQTYCGPTDNLSL 189
             ...|||...|:              .|.:|:.:|.|  ..||.....|.|
Worm   616 GMVERSNKYGST--------------AYCIGSEHHRP--YCYCKNQSKLEL 650

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeobox	256..309	CDD:278475
R03G8.3	NP_510174.3	DUF229	92..570	CDD:281053	15/76 (20%)
R03G8.3	NP_510174.3	ALP_like	190..480	CDD:293745
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0842
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900