Protein Alignment scro and Nkx6-1

DIOPT Version :9

• Sequence 1: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_659204.1
• Gene: Nkx6-1 / 18096
• MGIID: 1206039
• Length: 365
• Species: Mus musculus
• Alignment Length: 397
• Identity: 91/397 - (22%)
• Similarity: 143/397 - (36%)
• Gaps: 109/397 - (27%)

  Fly    32 PNEEDLVMSLSPKDTLIHTAISQHHQVDTST--------KLNTNETSTQNTVSTAAAAAVAHHHH 88
            |.:...::|..|...|       |...:..|        .|.|...|:.::.|::::.:.....|
Mouse    10 PRQSAFLLSSPPLAAL-------HSMAEMKTPLYPAAYPPLPTGPPSSSSSSSSSSSPSPPLGSH 67

  Fly    89 NLSSIH-----HLQNLHSQHQSTLFNSNHSTPFSVTDILS----PIEESYRKLELNGNPPSPFRS 144
            |...:.     .|.:|.|..|..    :.:||..:.||||    |:...   ..|....||...|
Mouse    68 NPGGLKPPAAGGLSSLGSPPQQL----SAATPHGINDILSRPSMPVASG---AALPSASPSGSSS 125

  Fly   145 NSSSS-------------------SINSPGTLTT-----STMANPYAMGTLYHSPGVQTYCG--- 182
            :||||                   :.:||..|..     |:::.|.....||.||.......
Mouse   126 SSSSSASATSASAAAAAAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPPGLYFSPSAAAVAAVGR 190

  Fly   183 -PTDNLSLAGHYTDMRNSASWYGSTANDPRFAISRLMSSSASGTMSHMGNMSGLAACSVSDSKPL 246
             |.....|.|     |....|.| ....|.:..:||                   ||:......|
Mouse   191 YPKPLAELPG-----RTPIFWPG-VMQSPPWRDARL-------------------ACTPHQGSIL 230

  Fly   247 QFPLAQRRKRRVLFTQAQVYELERRFKQQRYLSAPEREHLASLIHLTPTQVKIWFQNHRYKC-KR 310
            .....:|:..|..|:..|::.||:.|:|.:||:.|||..||..:.:|.:|||:||||.|.|. |:
Mouse   231 LDKDGKRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKK 295

  Fly   311 QAKEKAMAEQNQHNQ----------------------PASSPRRVAVPVLVKDGKPCSGNNSSSQ 353
            .|.|.|.|::.|.::                      |.|...::.  .|:|..|...|:.....
Mouse   296 HAAEMATAKKKQDSETERLKGTSENEEDDDDYNKPLDPNSDDEKIT--QLLKKHKSSGGSLLLHA 358

  Fly   354 SQQHGTN 360
            |:..|::
Mouse   359 SEAEGSS 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeobox	256..309	CDD:278475	24/53 (45%)
Nkx6-1	NP_659204.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	35..136		25/107 (23%)
		Repressor domain. /evidence=ECO:0000250	102..269		45/194 (23%)
		Homeobox	240..293	CDD:278475	24/52 (46%)
		DUF3381	<291..345	CDD:288694	10/55 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	295..365		13/71 (18%)
		Involved in DNA-binding. /evidence=ECO:0000250	307..365		9/59 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833345
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840