Protein Alignment scro and Nkx2-6

DIOPT Version :9

• Sequence 1: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_035050.2
• Gene: Nkx2-6 / 18092
• MGIID: 97351
• Length: 289
• Species: Mus musculus
• Alignment Length: 345
• Identity: 115/345 - (33%)
• Similarity: 143/345 - (41%)
• Gaps: 109/345 - (31%)

  Fly   113 STPFSVTDIL-----SPIEESYRKLELNGNPPSP--FRSNSSSSSINS-------PGTLTTSTM- 162
            ||||||.|||     ....::..:.||:.||..|  .|.|..|....|       |...|..|:
Mouse     8 STPFSVADILRLECQQKDSKTLSQWELHRNPVKPRYLRMNQESGWFESSDRAQAVPFRCTWETVL 72

  Fly   163 ---ANPYAMGTLYHSPGVQTYCGPTDNLSLAGHYTDMRNSASWYGSTANDPRFAISRLMSSSASG 224
               :||  :|.....||                                    .||||   .|..
Mouse    73 EMGSNP--VGEPQTPPG------------------------------------TISRL---GARN 96

  Fly   225 TMSH--MGNMSGLAACSVSDSKPLQFPLAQRRKRRVLFTQAQVYELERRFKQQRYLSAPEREHLA 287
            .|:.  :||:||    .:....|:......:||.||||:||||..|||||||||||:||||||||
Mouse    97 PMTDRGVGNLSG----DMRRGGPVSTRTRPQRKSRVLFSQAQVLALERRFKQQRYLTAPEREHLA 157

  Fly   288 SLIHLTPTQVKIWFQNHRYKCKRQAKEKAMAEQNQHNQPASSPRRVAVPVLVKDGKPC------- 345
            |.:.||.|||||||||.|||.|.|.:::.: |...|   ..:||||||||||.|||||
Mouse   158 SALQLTSTQVKIWFQNRRYKSKSQRQDQTL-ELAGH---PLAPRRVAVPVLVLDGKPCLDPDVAA 218

  Fly   346 --------------SGNNSSSQSQQHGTNSTSA----GNNTGSANNGNANSGIVSVTANVSGGLN 392
                          .|...:.....:.:..|||    |..|..|::|.:..|
Mouse   219 FLGPYKATSPYSCFGGYAGTPYDASYASRCTSASAGPGPLTPLASSGFSPGG------------- 270

  Fly   393 LITGDAPNSHSPDTSSSLLA 412
              ...||..|.|.|...:.|
Mouse   271 --QSAAPQGHLPATPQGVTA 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeobox	256..309	CDD:278475	42/52 (81%)
Nkx2-6	NP_035050.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	75..125		16/94 (17%)
		Homeobox	126..179	CDD:278475	42/52 (81%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	259..289		10/45 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833347
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0842
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740