Protein Alignment scro and DLX6

DIOPT Version :10

• Sequence 1: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_005213.3
• Gene: DLX6 / 1750
• HGNCID: 2919
• Length: 293
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 67/265 - (25%)
• Similarity: 101/265 - (38%)
• Gaps: 93/265 - (35%)

  Fly    76 STAAAAAVAHHHHNLSSIHHLQNLHSQHQSTLFNSNHSTPFSVTDILSPIEESYRKLELNGNPPS 140
            :.|||||.:||||           |.||.      :|.:|:
Human    77 AAAAAAAGSHHHH-----------HHQHH------HHGSPY------------------------ 100

  Fly   141 PFRSNSSSSSINSPGTLTTSTMANPYAMGTLYHSPGVQTYCGPTDNLSLAGHYTDMRNSASWYGS 205
               ::...:|.|.     .|..|.|| |....|||.:|:|...:......|..||.:.:
Human   101 ---ASGGGNSYNH-----RSLAAYPY-MSHSQHSPYLQSYHNSSAAAQTRGDDTDQQKT------ 150

  Fly   206 TANDPRFAISRLMSSSASGTMSHMGNMSGLAACSVSDSKPLQFPLAQR--RKRRVLFTQAQVYEL 268
                                             :|.::..::|....:  ||.|.:::..|:..|
Human   151 ---------------------------------TVIENGEIRFNGKGKKIRKPRTIYSSLQLQAL 182

  Fly   269 ERRFKQQRYLSAPEREHLASLIHLTPTQVKIWFQNHRYKCKRQAKEKAMAEQNQ--HNQPASSPR 331
            ..||:|.:||:.|||..||:.:.||.|||||||||.|.|.|:..|:.:...::.  ....|.|||
Human   183 NHRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLLKQGSNPHESDPLQGSAALSPR 247

  Fly   332 RVAVP 336
            ..|:|
Human   248 SPALP 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeodomain	254..310	CDD:459649	28/55 (51%)
DLX6	NP_005213.3	Homeodomain	168..224	CDD:459649	28/55 (51%)