Protein Alignment scro and DLX4

DIOPT Version :10

• Sequence 1: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_612138.1
• Gene: DLX4 / 1748
• HGNCID: 2917
• Length: 240
• Species: Homo sapiens
• Alignment Length: 242
• Identity: 71/242 - (29%)
• Similarity: 104/242 - (42%)
• Gaps: 32/242 - (13%)

  Fly   139 PSPFRSNSSSSSINSPGTLTTSTMANPYAMG---TLYHSPGVQTYCGPTDNLSLAGHYTDMRNSA 200
            |.|.....:|.:: .|......::|..|.:|   |...||.: :|..|..:| |:..||:..|..
Human     5 PCPLPGRDASKAV-FPDLAPVPSVAAAYPLGLSPTTAASPNL-SYSRPYGHL-LSYPYTEPANPG 66

  Fly   201 SWYGSTANDPRFAISRLMSSSASGTMSHMGNMSG-----LAACSVSDSKPLQFPLAQRRKRRVLF 260
            ..|.| ...|     ..:|....|...|...:..     ..:...|:.:| |.|..:.||.|.::
Human    67 DSYLS-CQQP-----AALSQPLCGPAEHPQELEADSEKPRLSPEPSERRP-QAPAKKLRKPRTIY 124

  Fly   261 TQAQVYELERRFKQQRYLSAPEREHLASLIHLTPTQVKIWFQNHRYKCKRQAKEKAMAEQNQHNQ 325
            :..|:..|.:||:..:||:.|||..||:.:.||.|||||||||.|      :|.|.:.:||...|
Human   125 SSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKR------SKYKKLLKQNSGGQ 183

  Fly   326 PASSPRRVAVPVLVKDGKPCSGNNSSS-QSQQHGTNSTSA-GNNTGS 370
            ....|.|..      ...|||....|. ...:.||..||. ||:.|:
Human   184 EGDFPGRTF------SVSPCSPPLPSLWDLPKAGTLPTSGYGNSFGA 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeodomain	254..310	CDD:459649	26/55 (47%)
DLX4	NP_612138.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	80..120		7/40 (18%)
		Homeodomain	118..174	CDD:459649	27/61 (44%)