Protein Alignment scro and Lbx1

DIOPT Version :10

• Sequence 1: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_034821.2
• Gene: Lbx1 / 16814
• MGIID: 104867
• Length: 282
• Species: Mus musculus
• Alignment Length: 245
• Identity: 77/245 - (31%)
• Similarity: 100/245 - (40%)
• Gaps: 58/245 - (23%)

  Fly   109 NSNHS-TPFSVTDILSPIEESYRKLELNGNPPSPFRSNSSSSSINSPGTLTTSTMANPYAMGTLY 172
            |||.. ||||:.|||              |.||..||.|..      |.......|:.
Mouse    28 NSNKPLTPFSIEDIL--------------NKPSVRRSYSLC------GAAHLLAAADK------- 65

  Fly   173 HSPGVQTYCGPTDNLSLAGHYTDMRNSASWYGSTANDPRFAISRLMSSSASGTMSHMGNMSGLAA 237
            |:||         .|.|||.....:.|          |..|:..|.|.:..|.     .:|.|.|
Mouse    66 HAPG---------GLPLAGRALLSQTS----------PLCALEELASKTFKGL-----EVSVLQA 106

  Fly   238 CSVSDSKPL----QFPLAQRRKRRVLFTQAQVYELERRFKQQRYLSAPEREHLASLIHLTPTQVK 298
            ....|...:    |.| .:|||.|..||..|:||||:||..|:|||..:|:.:|..:.||..||.
Mouse   107 AEGRDGMTIFGQRQTP-KKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVI 170

  Fly   299 IWFQNHRYKCKRQAKE-KAMAEQNQHNQPASSPRRVAVPVLVKDGKPCSG 347
            .||||.|.|.||..:| ||..|..:...|:.....||:..|.::.:...|
Mouse   171 TWFQNRRAKLKRDLEEMKADVESAKKLGPSGQMDIVALAELEQNSEASGG 220

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeodomain	254..310	CDD:459649	28/55 (51%)
Lbx1	NP_034821.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..36		4/7 (57%)
		Homeodomain	126..182	CDD:459649	28/55 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	210..282		2/11 (18%)