Protein Alignment scro and Hoxb5

DIOPT Version :10

• Sequence 1: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_032294.2
• Gene: Hoxb5 / 15413
• MGIID: 96186
• Length: 269
• Species: Mus musculus
• Alignment Length: 222
• Identity: 59/222 - (26%)
• Similarity: 93/222 - (41%)
• Gaps: 59/222 - (26%)

  Fly   125 IEESYRKLELNGNPPSPFRSNSSSSSINSPGTLT----TSTMANPYAMGTLYHSPGVQTYCGPTD 185
            :.||.|....:...|. ||..:||.|::||.:|.    .|..|.|.|             ..|:|
Mouse    69 VGESSRAFPASAQEPR-FRQATSSCSLSSPESLPCTNGDSHGAKPSA-------------SSPSD 119

  Fly   186 N---LSLAGHYTDMRNSASWYGSTANDPRFAISRLMSSS---------ASGTMSHMGNMSGLAAC 238
            .   .|.:.::|::..:     |.:::|..|.|:|.|.|         |:.|.:..|
Mouse   120 QATPASSSANFTEIDEA-----SASSEPEEAASQLSSPSLARAQPEPMATSTAAPEG-------- 171

  Fly   239 SVSDSKPLQFPLAQR------------RKRRVLFTQAQVYELERRFKQQRYLSAPEREHLASLIH 291
                ..|..||..::            ::.|..:|:.|..|||:.|...|||:...|..:|..:.
Mouse   172 ----QTPQIFPWMRKLHISHDMTGPDGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALC 232

  Fly   292 LTPTQVKIWFQNHRYKCKRQAKEKAMA 318
            |:..|:||||||.|.|.|:..|.|:|:
Mouse   233 LSERQIKIWFQNRRMKWKKDNKLKSMS 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeodomain	254..310	CDD:459649	22/55 (40%)
Hoxb5	NP_032294.2	PRK07003	<67..>171	CDD:235906	29/120 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	75..173		27/128 (21%)
		Antp-type hexapeptide	176..181		2/4 (50%)
		Homeodomain	195..251	CDD:459649	22/55 (40%)